Decreased half-life of insulin-like growth factor I in Rabson-Mendenhall syndrome

Journal of Inherited Metabolic Disease

Volumn 24, Issue 5, 2001, Pages 546-550

  Longo, N ^a   Singh, R ^a   Elsas, L J ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; RECOMBINANT PROTEIN; SOMATOMEDIN BINDING PROTEIN 3;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; AUTOSOMAL RECESSIVE INHERITANCE; CASE REPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION FUNCTION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG HALF LIFE; GENE MUTATION; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; PRESCHOOL CHILD; SIGNAL TRANSDUCTION; TREATMENT FAILURE; ACANTHOSIS NIGRICANS; BLOOD; CHILD; GENETICS; HALF LIFE TIME; MALE; METABOLISM; MUTATION; SYNDROME;

ACANTHOSIS NIGRICANS; CHILD; CHILD, PRESCHOOL; HALF-LIFE; HUMAN; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MALE; MUTATION; RECEPTOR, INSULIN; RECOMBINANT PROTEINS; SUPPORT, U.S. GOV'T, P.H.S.; SYNDROME;

EID: 0035149558     PISSN: 01418955     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012411709972     Document Type: Article

References (10)

1. Effect of intravenous IGF-I in two patients with leprechaunism
2. Pharmacokinetics of recombinant human insulin-like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency
3. Trial of IGF-I therapy for patients with extreme insulin resistance syndromes
4. Insulin-like growth factors in pediatric health and disease
5. Impaired growth in Rabson-Mendenhall syndrome: Lack of effect of growth hormone and IGF-I
6. Progressive decline in insulin levels in Rabson-Mendenhall syndrome
7. Long-term effect of recombinant human IGF-I on metabolic and growth control in a patient with leprechaunism
8. Leprechaunism and homozygous nonsense mutation in the insulin receptor gene
9. Acute response to recombinant IGF-I in a patient with Mendenhall's syndrome
10. rhIGF-I reduces hyperglycaemia in patients with extreme insulin resistance