The discovery of thiamethoxam: A second-generation neonicotinoid

Pest Management Science

Volumn 57, Issue 2, 2001, Pages 165-176

  Maienfisch, Peter ^a   Huerlimann, Hanspeter ^a   Rindlisbacher, Alfred ^a   Gsell, Laurenz ^a   Dettwiler, Hansruedi ^a   Haettenschwiler, Joerg ^a   Sieger, Evelyne ^a   Walti, Markus ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

2 nit roimino hexahydro 1,3,5 triazines; 4 nitroimino 1,3,5 oxadiazinane s; 4 nitroimino 1,3,5 thiadiazinanes; Discovery; Insecticidal activity; Insecticide; Neonicotinoids; Structure activity relationships; Synthesis; Thiamethoxam

Indexed keywords

ANABASINE; HETEROCYCLIC COMPOUND; IMIDACLOPRID; IMIDAZOLE DERIVATIVE; INSECTICIDE; NITRO DERIVATIVE; OXAZINE DERIVATIVE; PESTICIDE RESIDUE; THIAMETHOXAM; UNCLASSIFIED DRUG; WATER;

ANIMAL; BIOASSAY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFERENCE PAPER; DRUG ACTIVITY; DRUG EFFICACY; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; INSECT; INSECT CONTROL; NONHUMAN; PEST CONTROL; PLANT; SOIL; SOIL TREATMENT; STRUCTURE ACTIVITY RELATION;

ANABASINE; ANIMALS; BIOLOGICAL ASSAY; CHEMISTRY, AGRICULTURAL; IMIDAZOLES; INSECT CONTROL; INSECTICIDES; MOLECULAR STRUCTURE; NITRO COMPOUNDS; OXAZINES; PESTICIDE RESIDUES; PLANTS; SOIL; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

HEXAPODA;

EID: 0035146209     PISSN: 1526498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1526-4998(200102)57:2<165::AID-PS289>3.0.CO;2-G     Document Type: Article

References (35)

1. Neonicotinoids - Mode of action and selectivity
2. Insecticidal 2-(nitromethylene)pyrrolidines, Ger Offen DE 2 321 522 (1973)
3. Insecticidal 2-(nitromethylene)piperidines, Ger Offen DE 2 321 523 (1973)
4. Nitromethylene insecticides
5. Chloronicotinyl insecticides: A success of the new chemistry
6. Nitromethylene derivatives, intermediates, and their preparation as insecticides, Eur Pat Appl EP 163 855 (1985)
7. Studies on acyclic nitroethene compounds. Part 2. Synthesis and insecticidal activity of acyclic nitroethene compounds containing a heteroarylmethylamino group
8. NI-25, a new type of systemic and broad spectrum insecticide
9. CGA 293′343: A novel, broad-spectrum neonicotinoid insecticide
10. CGA 293343: A novel broad-spectrum insecticide supporting sustainable agriculture worldwide
11. Synthesis and insecticidal activity of CGA 293 343 - A novel broad-spectrum insecticide
12. Preparation of (heterocyclylmethyl)imidazolines, -thiazolidines, -tetrahydropyrimidines, and -tetrahydrothiazines as insectidies, Eur Pat Appl EP 235 725 (1987)
13. Preparation of (pyridylmethyl)guanidines as insecticides, Eur Pat Appl EP 376 279 (1990)
14. Preparation of organonitro compounds as insecticides, Eur Pat Appl EP 375 907 (1990)
15. Guanidine derivatives as insecticides, Eur Pat Appl EP 418 199 (1991)
16. MTI-446: A novel systemic insect control compound
17. Alpha-unsaturated amines, particularly 1,1-diamino-2-nitroethylene derivatives, their insecticidal/miticidal compositions, and processes for their preparation, Eur Pat Appl EP 302 389 (1989)
18. Preparation of pyridylalkylamine derivatives as insecticides, PCT Int Appl WO9 104 965 (1991)
19. The preparation and reactions of 2-alkyl-1 (or -3)-nitro-2-thiopseudourea. Part 1. Reactions with amines
20. Heterocyclic compounds, Eur Pat Appl EP 192 060 (1986)
21. 3H] Imidacloprid: Synthesis of a candidate radioligand for the nicotinic acetylcholine receptor
22. Synthetic approaches towards CGA 293 343: A novel broad-spectrum insecticide
23. The convergent synthesis of polyether ionophore antibiotics: The synthesis of the A ring carbamonensin spiro ether
24. Preparation of 2-(nitroimino)-1,3,5-triazacyclohexane pesticides, Eur Pat Appl EP 483 055 (1992)
25. A novel synthesis for the preparation of N, N′-disubstituted-N″-nitroguanidines, including a practical synthesis of the neonicotinoid insecticide clothianidin
26. Preparation of heterocyclic compounds as insecticides, Eur Pat Appl EP 386 565 (1990)
27. Preparation of triazine derivatives as insecticides, PCT Int Appl WO 9 101 978 (1991)
28. Preparation of hexahydrotriazine compounds as insecticides, Eur Pat Appl EP 428 941 (1991)
29. Synthesis of polynitro compounds from nitroguanidine
30. The reaction of N″-cyanoguanidine with formaldehyde. IV. The formation pathway of 4-cyanoimino-3-(methoxymethyl)perhydro-1,3,5-oxadiazine
31. Preparation of 3-(heterocyclylmethyl)-4-iminoperhydro-1,3,5-oxadiazine derivatives as pesticides, Eur Pat Appl EP 580 553 (1994)
32. Preparation of nitroiminotetrahydrooxadiazines as insecticides, Jpn Pat Appl JP 07 224 062 (1995)
33. Preparation of 5-(tetrahydrofuran-3-yl)methyl-4-nitroiminoperhydro-1,3,5-oxadiaz ine derivatives as insecticides, Jpn Pat Appl JP 08 291 171 (1996)