Inhibition of volume-regulated anion channels in cultured endothelial cells by the anti-oestrogens clomiphene and nafoxidine

British Journal of Pharmacology

Volumn 132, Issue 1, 2001, Pages 135-142

  Maertens, Chantal ^a   Droogmans, Guy ^a   Chakraborty, Prabir ^b   Nilius, Bernd ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Anti oestrogens; Clomiphene; Enclomiphene; Endothelial cells; ICI 182,780; Nafoxidine; RU 58,668; Volume regulated anion channels; Zuclomiphene; estradiol

Indexed keywords

11 [4 [[5 [(4,4,5,5,5 PENTAFLUOROPENTYL)SULFONYL]PENTYL]OXY]PHENYL]ESTRADIOL; ANION CHANNEL; ANTIESTROGEN; CHLORIDE; CLOMIFENE; ENCLOMIFENE; ESTRADIOL; FULVESTRANT; NAFOXIDINE; ZUCLOMIFENE;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; ENANTIOMER; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PATCH CLAMP; PRIORITY JOURNAL;

EID: 0035144676     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703786     Document Type: Article

References (29)

1. Antiangiogenic tumour therapy: Will it work?
2. Intrauterine exposure to clomiphene and neonatal persistent hyperplastic primary vitreous
3. Nafoxidine modulates the expression of matrix-metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinases-(TIMP-1) in endothelial cells
4. Volume-activated chloride channels in neuroblastoma cells are blocked by the anti-oestrogen toremifene
5. Inhibition of angiogenesis by anti-oestrogens
6. Anti-oestrogens inhibit endothelial cell growth stimulated by angiogenic growth factors
7. The gonadal hormones and inhibitors
8. Clinical potential of new anti-oestrogens
9. - current activated by cell swelling in rabbit portal vein vascular smooth muscle cells
10. Endocrine fertility-restricting factors in clomiphene therapy
11. Swelling-activated organic osmolyte channels
12. Inhibition of angiogenesis by blockers of volume-regulated anion channels
13. Properties of volume-regulated anion channels in mammalian cells
14. - current by hypotonic volume increase in human endothelial cells
15. - channels in macrovascular endothelial cells
16. Calcium-activated chloride channels in bovine pulmonary artery endothelial cells
17. --currents in human endothelial cells
18. - currents in different mammalian non-excitable cell types
19. - channel: Fresh start to the molecular identity and volume sensor
20. Clomiphene citrate as a possible cause of a psychotic reaction during infertility treatment
21. Regulation of solute and water balance and cell volume in the central nervous system
22. Cellular and molecular physiology of volume-sensitive anion channels
23. 2+ concentration
24. Membrane currents and the resting membrane potential in cultured bovine pulmonary artery endothelial cells
25. - currents inhibit endothelial cell proliferation
26. - currents during muscle differentiation
27. Oestrogens and progestins
28. Lens opacification by antiooestrogens: Tamoxifen vs ICI 182,780
29. Tamoxifen blocks chloride channels. A possible mechanism for cataract formation