Association of distinct tetraspanins with MHC class II molecules at different subcellular locations in human immature dendritic cells

International Immunology

Volumn 13, Issue 2, 2001, Pages 127-134

  Engering, Anneke ^a,b   Pieters, Jean ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Antigen presentation; Antigen processing; Dendritic cells; MHC class II; MHC class II compartments; Tetraspanins

Indexed keywords

CD53 ANTIGEN; CD63 ANTIGEN; CD81 ANTIGEN; CD9 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; PEPTIDE; TETRASPANIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PURIFICATION; ARTICLE; CELL MATURATION; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; LYMPHOID ORGAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE ACTIVATION;

EID: 0035144246     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/13.2.127     Document Type: Article

References (53)

1. Origin, maturation and antigen presenting function of dendritic cells
2. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
3. The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells
4. Transient accumulation of new MHC molecules in a novel endocytic compartment in B lymphocytes
5. Isolation and characterization of the intracellular MHC class II compartment
6. Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells
7. Distinct intracellular compartments involved in invariant chain degradation and antigenic peptide loading of major histocompatibility complex (MHC) class II molecules
8. Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
9. Invaiant chain distinguishes between the exogenous and endogenous antigen presentation pathways
10. MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
11. Intracellular transport of class II MHC molecules directed by invariant chain
12. The MHC class II-associated invariant chain contains two endosomal sorting signals within its cytoplasmic tail
13. Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L
14. Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading
15. HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilities peptide loading
16. Mediation by HLA-DM of dissociation of peptides from HLA-DR
17. Transcriptional and posttranscriptional regulation of macrophage-specific colony stimulating factor gene expression by tumor necrosis factor
18. The tetraspanin superfamily: Molecular facilitators
19. CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins
20. Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY
21. Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins
22. Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
23. The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules
24. Intracellular pathway for the generation of functional MHC class II peptide complexes in immature human dendritic cells
25. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
26. Developmental regulation of MHC class II transport in mouse dendritic cells
27. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells
28. Efficient presentation of soluble antigen by cultured human dendritic cells in maintained by granulocyte/macrophage colony-stimulating factor plus interleukin-4 and downregulated by tumor necrosis factor-α
29. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
30. Cortisone-evoked decrease of acid β-galactosidase, β-glucuronidase, N-acetyl-β-glucosaminidase and acrylsulphatase in the ileum of suckling rats
31. High resolution two-dimensional electrophoresis of proteins
32. Use of large-scale two-dimensional ISODALT gel electrophoresis systems in immunology
33. Improved silver staining procedure for fast staining in PhastSystem development unit. I. Staining of sodium dodecyl sulfate gels
34. Intracellular transport and localization of Major Histocompatibility Complex class II molecules and associated invariant chain
35. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
36. Assembly and retention of CD1b heavy chains in the endoplasmic reticulum
37. Antigen presentation: Mixing oil and water
38. CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells
39. Segregation of MHC class II molecules from MHC Class I molecules in the Golgi complex for transport to lysosomal compartments
40. Antigen capture and MHC class II compartments of freshly isolated and cultures human blood dendritic cells
41. MHC class II restricted antigen presentation
42. How MHC class II molecules acquire peptide cargo: Biosynthesis and trafficking through the endocytic pathway
43. MHC Class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
44. B lymphocytes secrete antigen-presenting vesicles
45. Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73
46. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
47. The cell biology of CTL killing
48. CD63 is a component of Weibel-Palade bodies of human endothelial cells
49. Fc receptor-triggered insertion of secretory granules into the plasma membrane of human neutrophils: Selective retrieval during phagocytosis
50. Ultrastructural localization of Charcot-Leyden crystal protein in human eosinophils and basophils
51. Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules
52. Characterization of MHC class II compartments by immunoelectron microscopy