Spectrin: The ghost in the machine

BioEssays

Volumn 23, Issue 2, 2001, Pages 152-160

  Thomas, Graham H ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN; SPECTRIN;

ANIMAL; BIOLOGICAL MODEL; ERYTHROCYTE MEMBRANE; FORECASTING; HUMAN; METABOLISM; MORPHOGENESIS; PHYSIOLOGY; REVIEW;

ANIMALS; ERYTHROCYTE MEMBRANE; FORECASTING; HUMANS; MODELS, BIOLOGICAL; MORPHOGENESIS; MYOSINS; SPECTRIN;

EID: 0035143853     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-1878(200102)23:2<152::AID-BIES1022>3.0.CO;2-1     Document Type: Review

References (82)

1. The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane
2. Hereditary spherocytosis and hereditary elliptocytosis
3. The rote of ankyrin and spectrin in membrane transport and domain formation
4. Selective solubilization of a protein component of the red cell membrane
5. Mild spherocytosis and altered red cell ion transport in protein 4.2-null mice
6. Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton
7. Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice
8. New perspectives on mechanisms involved in generating epithelial cell polarity
9. Segregation of two spectrin isoforms: Polarized membrane-binding sites direct polarized membrane skeleton assembly
10. A-spectrin is required for ovarian follicle monolayer integrity in Drosphila melanogaster
11. H-spectrin is essential for development and contributes to specific cell fates in the eye
12. Apical spectrin is essential for epithelial morphogenesis but is not required for apicobasal polarity in Drosophila
13. Caenorhabditis elegans β-G spectrin is dispensibe for establishment of epithelial polarity, but essential for muscular and neuronal function
14. Cell shape and interaction defects in α-spectrin mutants of Drosophila melanogaster
15. Drosophila β spectrin functions independently of a spectrin to polarize the Na,K ATPase in epithelial cells
16. Heavy- spectrin required for C. elegans morphogenesis
17. Mutations in β-spectrin disrupt axon outgrowth and sarcomere structure
18. +-ATPase in polarized epithelial cells
19. Genetic analysis of the actin cytoskeleton in the Drosophila ovary
20. Drosophila development requires spectrin network formation
21. Caenorhabditis elegans morphogenesis: The role of the cytoskeleton in elongation of the embryo
22. sma 1 encodes an apically localized spectrin involved in C. elegans morphogenesis
23. Intragenic duplication and divergence in the spectrin superfamily of proteins
24. Transient, localized accumulation of alpha-spectrin during sea urchin morphogenesis
25. A potential role for spectrin during neurulation
26. Heavy-spectrin has a restricted tissue and sub cellular distribution during Drosophila embryogenesis
27. Epithelial morphogenesis
28. The cytoskeleton of the intestinal epitheliurn
29. Differential effects of myosin-antibody complexes on contractile rings and circumferential belts in εpitheliod cells
30. 2+ Ions
31. Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function
32. Drosophila nonmuscle myosin II has multiple essential roles in imaginal disc and egg chamber morphogenesis
33. Mechanisms of early Drosophila mesoderm formation
34. Regulation of the movement of solutes across tight junctions
35. Mechanisms of increased endothelial permeability
36. Location of a protein of the fodrinspectrin-TW260/240 family in the mouse intestinal brush border
37. Characterization of intestinal brush border cytoskeletal proteins of normal and neoplastic human epithelial cells
38. H) is similar in size to vertebrate dystrophin
39. F-actin-binding and cross-linking properties of porcine brain fodrin, a spectrin-related molecule
40. Dynamic rearrangment of the spectrin membrane skeleton during the generation of epithelial polarity in Drosophila
41. Human erythrocyte myosin: Identification and purification
42. Myosin from human erythrocytes
43. Regulation of actin filament length in erythrocytes and striated muscle
44. An actomyosin contractile mechanism for erythrocyte shape transformations
45. Calculation of a gap restoration in the membrane skeleton of the red blood cell: Possible role for myosin II in local repair
46. Isolation and characterization of a sea urchin zygote cortex that supports in vitro contraction and reactivation of furrowing
47. The membrane-based mechanism of cell motility in cochlear outer hair cells
48. Effects of actin filament cross-linking and filament length on actin-myosin interaction
49. Mechanochemistry of the alternatively spliced spectrin-actin binding domain in membrane skeletal protein 4.1
50. Erythrocyte protein 4.1 binds and regulates myosin
51. Contributions of the β-subunit to spectrin structure and function
52. An F-actin- and Calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin
53. H spectrin
54. Mechanisms of cytoskeletal regulation: Modulation of membrane affinity in avian brush border and erythrocyte spectrins
55. Studies on the spectrin-like protein from the intestinal brush border, TW260/240, and characterization of its interaction with the cytoskeleton and actin
56. Mechanism of brush border contractility studied by the quick-freeze, deep-etch method
57. A model of spectrin as a concertina in the erythrocyte membrane skeleton
58. Dependence of the mechanical properties of actin/α-actinin gels on deformation rate
59. Phosphorylation of adducin by Rho-kinase plays a crucial rote in cell motility
60. Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Mandin-Darby canine kidney epithelial cells
61. Human recombinant α-catenin binds to spectrin
62. Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure
63. A putative catenin-cadherin system mediates morphogenesis of the C. elegans embryo
64. The brush border cytoskeleton is not static: In vivo turnover of proteins
65. Cell shape changes during gastrulation in Drosophila
66. Gastrulation in Drosophila: The formation of the ventral furrow and posterior midgut invaginations
67. A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation
68. Signaling to the actin cytoskeleton
69. Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons
70. AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing
71. Erythrocyte spectrin is comprised of many homologous triple helical segments
72. Crystal structure of the repetitive segments of spectrin
73. Structures of two repeats of spectrin suggest models of flexibility
74. Properties of human red cell spectrin heterodimer (side-to-side) assembly and identification of an essential nucleation site
75. Location of the human red cell spectrin tetramer binding site and detection of a related "closed" hairpin loop dimer using proteolytic footprinting
76. Point mutation in the β-spectrin gene associated with αl/74 hereditary elliptocytosis
77. β spectrin in human skeletal muscle
78. Ankyrin binds to the 15th repetitive unit of erythroid and non-erythroid beta-spectrin
79. Developmental genetics of oogenesis
80. The embryonic cell lineage of the nematode Caenorhabditis elegans
81. Mutations of alpha spectrin and labial block cuprophilic cell differentiation and acid secretion in the middle midgut of Drosophila larvae
82. Quick-freeze, deep-etch visualization of the cytoskeleton beneath surface differentiations of intestinal epithelial cells