Specific neosaxitoxin interactions with the Na+ channel outer vestibule determined by mutant cycle analysis

Biophysical Journal

Volumn 80, Issue 2, 2001, Pages 698-706

  Penzotti, Jennifer L ^a   Lipkind, Gregory ^a   Fozzard, Harry A ^a   Dudley Jr , Samuel C ^b,c  

^a UNIVERSITY OF CHICAGO   (United States)

^b EMORY UNIVERSITY   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; FUNCTIONAL GROUP; GUANIDINE; HYDROXYL GROUP; MUTANT PROTEIN; NEOSAXITOXIN; SAXITOXIN; SODIUM CHANNEL; TYROSINE;

ALPHA CHAIN; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CHANNEL GATING; CONTROLLED STUDY; ENERGY TRANSFER; FEMALE; HYDROGEN BOND; MOLECULAR INTERACTION; NONHUMAN; PH; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTON TRANSPORT; RAT; TOXIN STRUCTURE;

ANIMALIA; RATTUS;

EID: 0035142987     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76049-3     Document Type: Article

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