Infectivity of Chlamydia trachomatis serovar LGV but not E is dependent on host cell heparan sulfate

Infection and Immunity

Volumn 69, Issue 2, 2001, Pages 968-976

  Taraktchoglou, M ^a   Pacey, A A ^a   Turnbull, J E ^a   Eley, A ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; HEPARAN SULFATE;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BACTERIAL VIRULENCE; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CHO CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEXUALLY TRANSMITTED DISEASE; STRAIN DIFFERENCE;

ANIMALS; CELL LINE; CHLAMYDIA TRACHOMATIS; CHO CELLS; CRICETINAE; FLOW CYTOMETRY; GLYCOSAMINOGLYCANS; HELA CELLS; HEPARIN; HEPARITIN SULFATE; HUMANS; MICE;

EID: 0035142611     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.2.968-976.2001     Document Type: Article

References (51)

1. Functions of cell surface heparan sulfate proteoglycans
2. Production method affects the pharmacokinetic and ex vivo biological properties of low molecular weight heparins
3. Genital chlamydial infections: Epidemiology and reproductive sequelae
4. Heparin-mediated inhibition of Chlamydia psittaci to HeLa cells
5. Trachoma and LGV biovars of Chlamydia trachomatis share the same glycosaminoglycan-dependent mechanism for infection of eukaryotic cells
6. Chlamydia trachomatis glycosaminoglycan-dependent and independent attachment to eukaryotic cells
7. Structural requirements of heparin binding to Chlamydia trachomatis
8. Diagnostic value of the polymerase chain reaction for Chlamydia detection as determined in a follow-up study
9. Low molecular weight heparins in acute coronary syndrome
10. Biology and pathology of the pericellular heparan sulfate proteoglycans
11. Developmental changes in heparan sulfate expression: In situ detection with mAbs
12. Differences in the association of Chlamydia trachomatis serovar E and serovar L2 with epithelial cells in vitro may reflect biological differences in vivo
13. Animal cell mutants defective in glycosaminoglycan biosynthesis
14. Low-molecular weight heparins: Pharamacologic profile and product differentiation
15. HSPG-expressing Neisseria gonorrhoeae into epithelial cells
16. Structure and function of heparan sulfate proteoglycans
17. Heparan sulphate proteoglycans
18. Cell biology
19. Hormonal modification of epithelial differentiation and expression of cell surface heparan sulfate proteoglycan in the mouse vaginal epithelium
20. Epithelial cells from human fallopian tube in culture
21. Sulphated carbohydrate compounds prevent microbial adherence by sexually transmitted disease pathogens
22. Expression of syndecan-1 in female reproductive tract tissues and cultured keratinocytes
23. 1
24. Dynamics of uterine glycoconjugate expression and function
25. Interaction of Chlamydia trachomatis organisms and HeLa 229 cells
26. Improved PCR sensitivity for direct genotyping of Chlamydia trachomatis serovars by using a nested PCR
27. A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis
28. Sperm interaction with human oviductal cells in vitro
29. Interaction of chlamydiae and the host cells in vitro
30. Chlamydia trachomatis: Impact on human reproduction
31. The interaction in vitro of human spermatozoa with epithelial cells from the human uterine (fallopian) tube
32. Chlamydia-dependent biosynthesis of a heparan sulfate-like compound in eukaryotic cells
33. Microbial adherence to and invasion through proteoglycans
34. Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
35. Comparison of low molecular weight heparin (enoxaparin sodium) and standard unfractionated heparin for haemodialysis anticoagulation
36. Vaccines against Chlamydia: Approaches and progress
37. Chlamydia trachomatis infections of the adult
38. Molecular mimicry and Chlamydia trachomatis infection of eukaryotic cells
39. Eukaryotic cell uptake of heparin-coated microspheres: A model of host cell invasion by Chlamydia trachomatis
40. Sulfated polysaccharides and a synthetic sulfated polymer are potent inhibitors of Chlamydia trachomatis infectivity in vitro but lack protective effect in an in vivo model of chlamydial genital tract infection
41. Differential effect of trypsin on infectivity of Chlamydia trachomatis: Loss of infectivity requires cleavage of major outer membrane protein variable domains II and IV
42. Chlamydia trachomatis-host cell interactions: Role of the chlamydial major outer membrane protein as an adhesin
43. A recombinant Chlamydia trachomatis major outer membrane protein binds to heparan sulfate receptors on epithelial cells
44. Evidence that the major outer membrane protein of Chlamydia trachomatis is glycosylated
45. Binding of the glycan of the major outer membrane protein of Chlamydia trachomatis to HeLa cells
46. Molecular organisation of heparan sulfate from human skin fibroblasts
47. The effects of minidose heparin and low molecular weight heparin on peritonitis in the rat
48. Glycosaminoglycan-binding microbial proteins in tissue adhesion and invasion: Key events in microbial pathogenicity
49. Heparan sulfate is a cellular receptor for Chlamydia pneumoniae
50. Sulfated polyanions block Chlamydia trachomatis infection of cervix-derived human epithelia
51. Mechanism of Chlamydia trachomatis attachment to eukaryotic host cell