-
6
-
-
0032910345
-
Arsenic trioxide and interferon-alpha synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells
-
(1999)
Blood
, vol.93
, pp. 278-283
-
-
Bazarbachi, A.1
El-Sabban, M.E.2
Nasr, R.3
-
13
-
-
0029794132
-
A decade of molecular biology of retinoic acid receptors
-
(1996)
FASEB J
, vol.10
, pp. 940-954
-
-
Chambon, P.1
-
14
-
-
0030610686
-
Use of arsenic trioxide (As203) in the treatment of acute promyelocytic leukemia (APL): I. As203 exerts dose-dependent dual effects on APL cells
-
(1997)
Blood
, vol.89
, pp. 3345-3353
-
-
Chen, G.Q.1
Shi, X.G.2
Tang, W.3
-
15
-
-
0010740572
-
In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As203) in the treatment of acute promyelocytic leukemia: As203 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins
-
(1996)
Blood
, vol.88
, pp. 1052-1061
-
-
Chen, G.Q.1
Zhu, J.2
Shi, X.G.3
-
16
-
-
0027258363
-
Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia
-
(1993)
J Clin Invest
, vol.91
, pp. 2260-2267
-
-
Chen, S.J.1
Zelent, A.2
Tong, J.H.3
-
17
-
-
0027411688
-
Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukemia
-
(1993)
EMBO J
, vol.12
, pp. 1161-1167
-
-
Chen, Z.1
Brand, N.J.2
Chen, A.3
-
18
-
-
13044268455
-
Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6318-6323
-
-
Cheng, G.1
Zhu, X.2
Men, X.3
-
22
-
-
0025043959
-
The t(15;17) translocation of acute promyelocytic leukemia fuses the retinoic acid receptor α gene to a novel transcribed locus
-
(1990)
Nature
, vol.347
, pp. 558-561
-
-
De The, H.1
Chomienne, C.2
Lanotte, M.3
-
24
-
-
0032534679
-
Stimulation of Stat5 by granulocyte colony-stimulating factor (G-CSF) is modulated by two distinct cytoplasmic regions of the G-CSF receptor
-
(1998)
J Immunol
, vol.161
, pp. 6503-6509
-
-
Dong, F.1
Liu, X.2
De Koning, J.P.3
-
25
-
-
0026708201
-
Fetal hemoglobin levels in sickle cell disease and normal individuals are partially controlled by an X-linked gene located at Xp22.2
-
(1992)
Blood
, vol.80
, pp. 816-824
-
-
Dover, G.J.1
Smith, K.D.2
Chang, Y.C.3
-
29
-
-
0023684923
-
The nuclear matrix protein, numatrin (B23), is associated with growth factor-induced mitogenesis in Swiss 3T3 fibroblasts and with T lymphocyte proliferation stimulated by lectins and anti-T cell antigen receptor antibody
-
(1988)
J Cell Biol
, vol.107
, pp. 1629-1642
-
-
Feuerstein, N.1
Spiegel, S.2
Mond, J.3
-
35
-
-
0034663029
-
Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17); Results of the European Working Party. Groupe Francais de Cytogenetique Hematologique, Groupe de Francais d'Hematologie Cellulaire, UK Cancer Cytogenetics Group and BIOMED 1 European Community-Concerted Action "Molecular Cytogenetic Diagnosis in Haematological Malignancies"
-
(2000)
Blood
, vol.96
, pp. 1297-1308
-
-
Grimwade, D.1
Biondi, A.2
Mozziconacci, M.J.3
-
37
-
-
9444225115
-
Establishing the presence of the t(15;17) in suspected acute promyelocytic leukaemia: Cytogenetic, molecular and PML immunofluorescence assessment of patients entered into the M.R.C. ATRA trial. M.R.C. Adult Leukaemia Working Party
-
(1996)
Br J Haematol
, vol.94
, pp. 557-573
-
-
Grimwade, D.1
Howe, K.2
Langabeer, S.3
-
42
-
-
0032522962
-
Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia
-
(1998)
Blood
, vol.91
, pp. 2634-2642
-
-
Guidez, F.1
Ivins, S.2
Zhu, J.3
-
46
-
-
4243701391
-
Transcription therapy for cancer effects of histone deacetylase (HDAC) inhibitors on proliferation, apoptosis and differentiation of leukemic cell lines
-
abstr
-
(1998)
Blood
, vol.92
, Issue.SUPPL.
-
-
He, L.Z.1
Toletino, T.2
Warrell R.P., Jr.3
-
52
-
-
0026583943
-
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins
-
(1992)
EMBO J
, vol.11
, pp. 629-642
-
-
Kastner, P.1
Perez, A.2
Lutz, Y.3
-
53
-
-
0034144710
-
Leukemia initiated by PML-RARalpha: The PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable
-
(2000)
Blood
, vol.95
, pp. 1541-1550
-
-
Kogan, S.C.1
Hong, S.H.2
Shultz, D.B.3
-
56
-
-
0030930058
-
Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity
-
(1997)
Oncogene
, vol.15
, pp. 1275-1281
-
-
Kondo, T.1
Minamino, N.2
Nagamura-Inoue, T.3
-
63
-
-
0030612468
-
RAR alpha1/ RAR alpha2-PML mRNA expression in acute promyelocytic leukemia cells: A molecular and laboratory-clinical correlative study
-
(1997)
Blood
, vol.90
, pp. 306-312
-
-
Li, Y.P.1
Andersen, J.2
Zelent, A.3
-
64
-
-
0028899552
-
Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)
-
(1995)
Blood
, vol.85
, pp. 1083-1094
-
-
Licht, J.D.1
Chomienne, C.2
Goy, A.3
-
65
-
-
0033634946
-
Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers
-
(2000)
Mol Cell
, vol.5
, pp. 821-830
-
-
Lin, R.J.1
Evans, R.M.2
-
68
-
-
0025896251
-
Formation of nucleophosmin/ B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein
-
(1991)
Eur J Biochem
, vol.200
, pp. 715-721
-
-
Liu, Q.R.1
Chan, P.K.2
-
71
-
-
0033561797
-
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
-
(1999)
Blood
, vol.93
, pp. 3167-3215
-
-
Melnick, A.1
Licht, J.D.2
-
76
-
-
0032402135
-
Trivalent antimonials induce degradation of the PML-RAR oncoprotein and reorganization of the promyelocytic leukemia nuclear bodies in acute promyelocytic leukemia NB4 cells
-
(1998)
Blood
, vol.92
, pp. 4308-4316
-
-
Muller, S.1
Miller W.H., Jr.2
Dejean, A.3
-
77
-
-
0029803774
-
Interferon augments PML and PML/RARα expression in normal meyloid and acute promyelocytic cells and cooperates with all-trans-retinoic acid to induce maturation of a retinoid resistant promyelocytic cell line
-
(1996)
Blood
, vol.889
, pp. 3926-3936
-
-
Nason-Burchenal, K.1
Gandini, D.2
Botto, M.3
-
81
-
-
0031924709
-
Knocking in and out genes and trans genes: The use of the engineered mouse to study normal and aberrant hemopoiesis
-
(1998)
Semin Hematol
, vol.35
, pp. 136-148
-
-
Pandolfi, P.P.1
-
82
-
-
0025917413
-
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties
-
(1991)
Oncogene
, vol.6
, pp. 1285-1292
-
-
Pandolfi, P.P.1
Grignani, F.2
Alcalay, M.3
-
84
-
-
0026029528
-
Potentiation of retinoid-induced differentiation of HL-60 and U937 cell lines by cytokines
-
(1991)
Eur J Cancer
, vol.27
, pp. 53-57
-
-
Peck, R.1
Bollag, W.2
-
86
-
-
0009667404
-
Development of acute promyelocytic leukemia (APML) in transgenic mice expressing both the PML-RAR and the reciprocal fusion protein, RAR-PML
-
abstr
-
(1997)
Blood
, vol.90
, Issue.SUPPL.
-
-
Pollock, J.1
Grisolano, J.2
Goda, P.3
-
87
-
-
0030022316
-
The t(15;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
-
(1996)
Blood
, vol.3
, pp. 882-886
-
-
Redner, R.L.1
Rush, E.A.2
Faas, S.3
-
88
-
-
0034730198
-
Retinoic acid (RA) and As203 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10173-10178
-
-
Rego, E.M.1
He, L.Z.2
Warrell R.P., Jr.3
-
91
-
-
0028176437
-
The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells
-
(1994)
Oncogene
, vol.9
, pp. 545-551
-
-
Rousselot, P.1
Hardas, B.2
Patel, A.3
-
92
-
-
0034663180
-
A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlying PLZF/RARA gene rearrangements. Groupe Français de Cytogénétique Hématologique, UK Cancer Cytogenetics Group and BIOMED 1 European Community-Concerted Action "Molecular Cytogenetic Diagnosis in Haematological Malignancies"
-
(2000)
Blood
, vol.96
, pp. 1287-1296
-
-
Sainty, D.1
Liso, V.2
Cantu-Rajnoldi, A.3
-
98
-
-
0027258994
-
Occurrence of resistance to retinoic acid in the acute promyelocytic cell line NB4 is associated with altered expression of the PML/RARalpha protein
-
(1993)
Blood
, vol.82
, pp. 1573-1577
-
-
Dermine, S.1
Grignani, F.2
Clerici, M.3
-
99
-
-
0030610687
-
Use of arsenic trioxide (As203) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients
-
(1997)
Blood
, vol.89
, pp. 354-3360
-
-
Shen, Z.X.1
Chen, G.Q.2
Ni, J.H.3
-
105
-
-
0028980278
-
Persistence of RAR alpha-PML fusion mRNA detected by reverse transcriptase polymerase chain reaction in patients in long-term remission of acute promyelocytic leukaemia
-
(1995)
Br J Haematol
, vol.90
, pp. 615-618
-
-
Tobal, K.1
Saunders, M.J.2
Grey, M.R.3
-
106
-
-
0027078742
-
A mutated retinoic acid receptor-α exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line
-
(1992)
Genes Dev
, vol.6
, pp. 2258-2269
-
-
Tsai, S.1
Bartelmez, S.2
Heyman, R.3
-
111
-
-
0032170898
-
Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARalpha independent manner
-
(1998)
Blood
, vol.92
, pp. 1497-1504
-
-
Wang, Z.G.1
Rivi, R.2
Delva, L.3
-
119
-
-
4243529046
-
Efficient generation of acute promyelocytic leukemia in mice using a PML/ RARalpha cDNA "knocked in" to the murine cathepsin gene G locus requires Cre-mediated excision of a linked selectable marker cassette
-
abstr
-
(1998)
Blood
, vol.92
, Issue.SUPPL. 1
-
-
Westervelt, P.1
Ley, T.J.2
-
123
-
-
0029942879
-
Accelerated degradation of PML-retinoic acid receptor α (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: Possible role of the proteasome pathway
-
(1996)
Cancer Res
, vol.56
, pp. 2945-2948
-
-
Yoshida, H.1
Kitamura, K.2
Tanaka, K.3
-
125
-
-
0032721510
-
A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins
-
(1999)
Nat Genet
, vol.23
, pp. 287-295
-
-
Zhong, S.1
Delva, L.2
Rachez, C.3
|