Sumatriptan elicits both constriction and dilation in human and bovine brain intracortical arterioles

British Journal of Pharmacology

Volumn 132, Issue 1, 2001, Pages 55-62

  Elhusseiny, A ^a   Hamel, E ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Cerebral blood flow; Cerebral vessels; Endothelium; Migraine; Serotonin; Smooth muscle; Sumatriptan

Indexed keywords

1 [2 [4 (4 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N METHYLISOCHROMAN 6 CARBOXAMIDE; N (3 DIMETHYLAMINO 2,3,4,9 TETRAHYDRO 1H CARBAZOL 6 YL) 4 FLUOROBENZAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; SEROTONIN; SEROTONIN 1 AGONIST; SEROTONIN 1 ANTAGONIST; SEROTONIN 1D AGONIST; SEROTONIN 1F AGONIST; SUMATRIPTAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; BRAIN BLOOD FLOW; BRAIN CAPILLARY; BRAIN CIRCULATION; BRAIN CORTEX; CATTLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PIA ARTERY; PRIORITY JOURNAL; SEROTONIN RELEASE; VASOCONSTRICTION; VASODILATATION;

EID: 0035141465     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703763     Document Type: Article

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