Synthesis and evaluation of novel 2-oxo-1,2-dihydro-3-quinolinecarboxamide derivatives as potent and selective serotonin 5-HT4 receptor agonists

Chemical and Pharmaceutical Bulletin

Volumn 49, Issue 1, 2001, Pages 29-39

  Suzuki, M ^a   Ohuchi, Y ^a   Asanuma, H ^a   Kaneko, T ^a   Yokomori, S ^a   Ito, C ^a   Isobe, Y ^a   Muramatsu, M ^a  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Quinolinecarboxamide; Serotonin 5 HT4 receptor agonist; Structure activity relationship; TS 951

Indexed keywords

2 OXO 1,2 DIHYDRO 3 QUINOLINECARBOXAMIDE; AMIDE; SEROTONIN 5 RECEPTOR; SEROTONIN AGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DIGESTIVE SYSTEM FUNCTION DISORDER; DOG; DRUG ACTIVITY; DRUG POTENCY; GASTROINTESTINAL MOTILITY; GUINEA PIG; ILEUM; NONHUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMIDES; ANIMALS; DOGS; DRUG EVALUATION, PRECLINICAL; FEMALE; GASTROINTESTINAL MOTILITY; MALE; QUINOLINES; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN AGONISTS; SPECTRUM ANALYSIS;

EID: 0035141077     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.49.29     Document Type: Article

References (17)