Indomethacin activity in the fetal vasculature of normal and meconium exposed human placentae

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 94, Issue 2, 2001, Pages 230-233

  Holcberg, Gershon ^a   Sapir, Olga ^a   Huleihel, Mahmoud ^a,b   Katz, Miriam ^a   Bashiri, Asher ^a   Mazor, Moshe ^a   Malek, Antoine ^c   Tsadkin, Marina ^a   Schneider, Henning ^c  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c Universitats Frauenklinik   (Switzerland)

Author keywords

Indomethacin; Meconuium; Placental vasoconstrictive activity

Indexed keywords

INDOMETACIN;

ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; FEMALE; FETUS; FETUS CIRCULATION; HUMAN; HUMAN TISSUE; ISOLATED ORGAN; MECONIUM; PERFUSION PRESSURE; PLACENTA; PRIORITY JOURNAL; VASCULAR RESISTANCE; VASCULARIZATION; VASOCONSTRICTION;

EID: 0035140787     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-2115(00)00353-5     Document Type: Article

References (26)

1. Further study of the inhibition of premature labor by indomethacin. Part II: double blind study
2. Fetal and neonatal effects on indomethacin used as a tocolytic agent
3. Placental transfer of indomethacin in the human pregnancy
4. Indomethacin: studies of absorption and placental transfer
5. Indomethacin does not diminish the pulmonary vascular response of the fetus to increased oxygen tension
6. Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension
7. Meconium-stained amniotic fluid and risk for cerebral palsy in preterm infants
8. Amniotic fluid meconium: a fetal environmental hazard
9. Meconium-induced vasoconstriction: a potential cause of cerebral and other fetal hypoperfusion and of poor pregnancy outcome
10. The composition of meconium: isolation of blood group specific polysaccharides, abnormal composition of meconium in meconium ileus
11. In vitro model of human umbilical venous perfusion to study the effects of meconium staining of the umbilical cord
12. Effect of interleukin 8 in meconium on in-vitro neutrophil chemotaxis
13. Can meconium in amniotic fluid injure fetal brain?
14. Maternal and perinatal outcome of patients with preterm labor and meconium-stained amniotic fluid
15. Vasoconstrictive activity of meconium stained amniotic fluid in the human placental vasculature
16. Dual in vitro perfusion of an isolated lobe of human placenta: method and instrumentation
17. Spectrophotometric determination of meconium concentration in amniotic fluid
18. Neurohistochemical evidence supporting an absence of adrenergic and cholinergic innervation in the human placenta and umbilical cord
19. Current topic: control of vascular resistance in the human placenta
20. Effect of indomethacin on human placental steam villus arteries
21. Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy
22. Cyclooxygenase inhibitors blunt thromboxane action in humal placental arteries by blocking thromboxane receptors
23. Clinical pharmacokinetics of indomethacin
24. Meconium-induced umbilical cord vascular necrosis and ulceration: a potential link between the placenta and poor pregnancy outcome
25. Histopathologic effects of meconium on human umbilical artery and vein: in vitro study
26. Cyclooxygenase-2 expression in human monocytes stimulated by meconium