Hypothalamo-pituitary-adrenal axis testing: Nothing is sacred and caution in interpretation is needed

Clinical Endocrinology

Volumn 54, Issue 1, 2001, Pages 15-16

  Dickstein, Gabriel ^a  

^a BNAI ZION MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE; INSULIN; METYRAPONE;

ADRENAL INSUFFICIENCY; ADRENAL SUPPRESSION; CONTROLLED STUDY; CORTICOTROPIN TEST; GROWTH RETARDATION; HORMONE BLOOD LEVEL; HORMONE RESPONSE; HUMAN; HYPOGLYCEMIA; HYPOPHYSIS DISEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NOTE; PRIORITY JOURNAL;

ADRENAL CORTEX FUNCTION TESTS; ADRENAL INSUFFICIENCY; ADRENOCORTICOTROPIC HORMONE; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INSULIN; PITUITARY FUNCTION TESTS; PITUITARY-ADRENAL SYSTEM; PREDICTIVE VALUE OF TESTS;

EID: 0035138357     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2001.01185.x     Document Type: Note

References (15)

1. Comparison of one week 0900h serum cortisol, low and standard close Synacthen tests with 4-6 week insulin hypoglycaemia test after pituitary surgery in assessing HPA axis
2. The Insulin hypoglycaemia and overnight metyrapone test in the assessment of the hypothalamic-pituitary-adrenal axis following pituitary surgery
3. The low-dose (1 μg) ACTH test - When and how to use it
4. Low-dose ACTH stimulation test
5. Plasma corticotropin and cortisol responses to ovine CRH, AVP, CRH plus AVP and CRH plus metyrapone in patients with Cushing's disease
6. Establishment of reference values for standard dose short Synacthen test (250 μg), low dose short synacthen test (1 μg) and insulin tolerance test for the assessment of the hypothalamo-pituitary-adrenal axis in normal subjects
7. Adrenal suppresion, evaluated by the low dose adrenocorticotropin test, and growth in asthmatic children treated with inhaled steroids
8. Low dose (1 μg) ACTH test in the evaluation of adrenal dysfunction in pre-clinical Addison's disease
9. Adrenal responsiveness to high, low and very low ACTH 1-24 doses in obesity
10. Comparison of low and high dose corticotropin stimulation tests in patients with pituitary disease
11. The low ACTH stimulation test is less sensitive than the overnight metyrapone test for the diagnosis of secondary hypoadrenalism
12. Single dose metyrapone test
13. Low-dose (1 μg) adrenocorticotropin (ACTH) stimulation as a screening test for impaired hypothalamo-pituitaryadrenal axis function: Sensitivity, specificity and accuracy in comparison with the high-dose test
14. Dose-response relationship between plasma ACTH and serum cortisol in the insulin- hypoglycaemia test in 25 healthy subjects and 109 patients with pituitary disease
15. Reproducibility of growth hormone and cortisol responses to the insulin tolerance test and the short ACTH test in normal adults