Structural requirements for substrate recognition of Mycobacterium tuberculosis 14α-demethylase: Implications for sterol biosynthesis

Journal of Lipid Research

Volumn 42, Issue 1, 2001, Pages 128-136

  Bellamine, Aouatef ^a   Mangla, Anil T ^b,c   Dennis, Allen L ^b   Nes, W David ^b   Waterman, Michael R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS TECH UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

P 450; Sterol analogs; Substrate binding; Type I binding spectrum

Indexed keywords

CYTOCHROME P450; STEROL 14ALPHA DEMETHYLASE; STEROL DERIVATIVE; TRITERPENOID;

ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; STEROL SYNTHESIS;

CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; PROTEIN BINDING; SPECTRUM ANALYSIS; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRITERPENES;

EID: 0035137659     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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