Negative association of the HLA-DRB1*1502-DQB1*0601 haplotype with human narcolepsy

Immunogenetics

Volumn 52, Issue 3-4, 2001, Pages 299-301

  Hohjoh, Hirohiko ^a   Terada, Natsuko ^a   Honda, Yutaka ^b   Juji, Takeo ^c   Tokunaga, katsushi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SEIWA HOSPITAL   (Japan)

^c JAPANESE RED CROSS MEDICAL CENTER   (Japan)

Author keywords

1502; DRB1; Narcolepsy; Negative association

Indexed keywords

HLA DQ ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CATAPLEXY; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE ISOLATION; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; NARCOLEPSY; PRIORITY JOURNAL;

ALLELES; CHI-SQUARE DISTRIBUTION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; JAPAN; LINKAGE DISEQUILIBRIUM; NARCOLEPSY; ODDS RATIO;

EID: 0035136318     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510000269     Document Type: Article

References (13)

1. Discrimination of human HLA-DRB1 alleles by PCR-SSCP (single-strand conformation polymorphism) method
2. HLA class II alleles in Ainu living in Hidaka district. Hokkaido, northern Japan
3. Significant association of a single nucleotide polymorphism in the tumor necrosis factor-alpha (TNF-α) gene promoter with human narcolepsy
4. Genetic aspects of narcolepsy
5. Allele and haplotype frequencies for HLA and complement loci in various ethnic groups
6. HLA antigens in Japanese patients with narcolepsy: All the patients were DR2 positive
7. Routine low resolution and high resolution typing of HLA-DRB gene using PCR-MPH (microtiter plate hybridization) method
8. Genetic markers in narcolepsy
9. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
10. HLA class II nucleotide sequences, 1992
11. Human histocompatibility leukocyte antigen (HLA) haplotype frequencies estimated from the data on HLA class I, II, and III antigens in 111 Japanese narcoleptics
12. HLA DQBi-0602 is associated with cataplexy in 509 narcoleptic patients
13. Sequence-based association analysis of HLA class I and II alleles in Japanese supports conservation of common haplotypes