Prediction of metabolic activity from genotype: The gene-dose effect of N-acetyltransferase

Therapeutic Drug Monitoring

Volumn 23, Issue 1, 2001, Pages 9-14

  Meisel, Peter ^a   Arndt, Dorit ^a   Scheuch, Eberhard ^a   Klebingat, Klaus Jürgen ^a   Siegmund, Werner ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Arylamine N acetyltransferase; Genotype; Human liver; Phenotype; Polymorphism

Indexed keywords

ACYLTRANSFERASE; SULFADIMIDINE;

ACETYLATION; ACETYLATOR PHENOTYPE; ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; GENE DOSAGE; GENE MUTATION; GENOTYPE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LIVER CYTOSOL; MALE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADULT; ARYLAMINE N-ACETYLTRANSFERASE; FEMALE; GENOTYPE; HUMANS; LIVER; MALE; MUTATION; PHENOTYPE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0035135858     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200102000-00003     Document Type: Article

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13. Multiple linear regression is a useful alternative to traditional analysis of variance
14. NAT2*12A (803A-G) codes for rapid arylamine N-acetylation in humans
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16. Polymorphic N-acetylation of sulfamethazine and benzidine by human liver: Implication for cancer risk?