Stimulation of human albumin synthesis and gene expression by growth hormone treatment

Clinical Nutrition

Volumn 20, Issue 1, 2001, Pages 59-67

  Barle, H ^a   Rahlen L ^a   Essen P ^a   McNurlan, M A ^a   Garlick, P J ^b   Holgersson, J ^a   Wernerman, J ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Albumin; Gene expression; Growth hormone; Masspectrometry; Protein; RT PCR; Surgery

Indexed keywords

DEUTERIUM; HUMAN ALBUMIN; HUMAN GROWTH HORMONE; LIVER PROTEIN; MESSENGER RNA; PHENYLALANINE;

ADULT; AGED; ARTICLE; CHOLECYSTECTOMY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ELECTIVE SURGERY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER BIOPSY; MALE; POLYMERASE CHAIN REACTION; PROTEIN SYNTHESIS; QUANTITATIVE ASSAY; RANDOMIZED CONTROLLED TRIAL; SHORT COURSE THERAPY;

EID: 0035135274     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1054/clnu.2000.0158     Document Type: Article

References (51)

1. Induction of plasma protein synthesis in response to trauma
2. Reprioritization of liver protein synthesis resulting from recombinant human growth hormone supplementation in parenterally fed trauma patients: The effect of growth hormone on the acute-phase response
3. Increased vascular permeability: A major cause of hypoalbuminemia in disease and injury
4. Liver export proteins and trauma
5. Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation
6. Tissue protein synthesis rates in the critically ill
7. Albumin and fibrinogen synthesis rates increase while muscle protein synthesis decreases in head-injured patients
8. Time course of changes in albumin synthesis and mRNA in diabetic and insulin-trated rats
9. Fibrinogen and albumin synthesis are regulated at the transcriptional level during the acute phase response
10. Regulation of acute phase gene expression following surgery and endotoxin administration in the anesthetized pig
11. Albumin mRNA expression in human liver diseases and its correlation to serum albumin concentration
12. In situ hybridization of album in mRNA in normal liver and liver tumors: Identification of hepatocellular origin
13. Analysis of cytokine mRNA and DNA: Detection and quantification by competitive polymerase chain reaction
14. Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control
15. Depression of liver protein synthesis during surgery is prevented by growth hormone
16. Effect of hypophysectomy on the synthesis of rat liver albumin
17. Synthesis and secretion of rat albumin in vivo, in perfused rat liver and isolated hepatocytes
18. Effect of hypophysectomy and growth hormone treatment on albumin mRNA levels in the rat liver
19. Albumin synthesis and bone collagen formation in human immunodeficiency virus-positive subjects: Differential effects of growth hormone administration
20. Meal stimulation of albumin synthesis: A significant contributor to whole body protein synthesis in humans
21. Growth hormone administration in older adults: Effects on albumin synthesis
22. The concentrations of free amino acids in human liver tissue obtained during laparoscopic surgery
23. The synthesis rates of total liver protein and plasma albumin determined simultaneously in vivo in man
24. Quantitative PCR with internal controls
25. A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha (1, 3/1, 4)fucosyltransferase
26. A LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2
27. 5]-phenylalanine
28. The effects of short-term parenteral nutrition on human liver protein and amino acid metabolism during laparoscopic surgery
29. Solubility of albumin in alcohol after precipitation by trichloroacetic acid: A simplified procedure for separation of albumin
30. Comparison of acid ethanol extraction and acid gel filtration prior to IGF-I and IGF-II radioimmunoassays: Improvement of determinations in acid ethanol extracts by the use of truncated IGF-I as radioligand
31. Effects of dexamethasone on glucose-induced insulin and proinsulin release in low and high responders
32. Measurement of albumin synthesis in humans: A new approach employing stable isotopes
33. Positive nitrogen balance with growth hormone and hypocaloric intravenous feeding
34. Growth hormone stimulates protein synthesis during hypocaloric parenteral nutrition
35. Postoperative nitrogen balance with intravenous hyponutrition and growth hormone
36. Low-dose growth hormone and hypocaloric nutrition attenuate the protein-catabolic response after major operation
37. Effects of recombinant human growth hormone on donor-site healing in severely burned children
38. Metabolic effects of recombinant human growth hormone: Isotopic studies in the postabsorptive state and during parenteral nutrition
39. Effects of recombinant human growth hormone in patients with severe sepsis
40. Biosynthetic human growth hormone preserves both muscle protein synthesis and the decrease in muscle-free glutamine, and improves whole body nitrogen economy after operation
41. Insulin like growth factor I production is inhibited in human sepsis
42. Resistance of nitrogen metabolism to growth hormone treatment in the early phase after injury of patients with multiple injuries
43. Increased mortality associated with growth hormone treatment in critically ill adults
44. Acquired growth hormone resistance
45. The effect of dietary protein deficiency on albumin synthesis and on the concentration of active albumin messenger ribonucleic acid in rat liver
46. Correlation of albumin production rates and albumin mRNA levels in livers of normal, diabetic, and insulin-treated diabetic rats
47. Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: Distinction in mode action from stimulation of DNA synthesis
48. Post-transcritptional regulation of albumin gene expression in Xenopus liver
49. Regulation of translation initiation following stress
50. Application of recombinant DNA technology in gastrointestinal medicine and hepatology: Basic paradigms of molecular cell biology. Part B: Eukaryotic gene transcription and post-transcriptional RNA processing
51. Inhibition of liver protien synthesis during laparoscopic surgery