Different clinical characteristics of aminoglycoside-induced profound deafness with and without the 1555 A→G mitochondrial mutation

ORL

Volumn 63, Issue 1, 2001, Pages 25-30

  Tono, Tetsuya ^a   Kiyomizu, Kensuke ^a   Matsuda, Keiji ^a   Komune, Shizuo ^a   Usami, Shin Ichi ^b   Abe, Satoko ^c   Shinkawa, Hideichi ^c  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HIROSAKI UNIVERSITY   (Japan)

Author keywords

Aminoglycoside; Cochlear implantation; Mitochondria; Ototoxicity; Point mutation; Sensorineural hearing loss

Indexed keywords

ADENINE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; GUANINE; MITOCHONDRIAL DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; AUDITORY STIMULATION; AUDITORY THRESHOLD; CLINICAL FEATURE; COCHLEA PROSTHESIS; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GENE MUTATION; GENETIC SUSCEPTIBILITY; HEARING LOSS; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEIC ACID BASE SUBSTITUTION; OTOTOXICITY; PATHOGENESIS; PEDIGREE ANALYSIS; PRIORITY JOURNAL; PURE TONE AUDIOMETRY; VESTIBULAR FUNCTION;

AGED; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; AUDIOMETRY, PURE-TONE; DEAFNESS; DNA, MITOCHONDRIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; PEDIGREE;

EID: 0035134021     PISSN: 03011569     EISSN: None     Source Type: Journal    
DOI: 10.1159/000055702     Document Type: Article

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