Autoradiographic localisation and contractile properties of prostatic endothelin receptors in patients with bladder outlet obstruction

European Urology

Volumn 39, Issue 1, 2001, Pages 48-56

  Mumtaz, F H ^a,c   Dashwood, M R ^a   Thompson, C S ^a   Khan, M A ^a   Naylor, A M ^b   Mikhailidis, D P ^a   Morgan, R J ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Benign prostatic hyperplasia; Endothelin receptors (ETA and ETB)

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N (HEXAHYDRO 1 AZEPINYLCARBONYL)LEUCYL(1 METHYL DEXTRO TRYPTOPHYL) DEXTRO TYROSINE; N ACETYLENDOTHELIN 1 [6-21][11,15 ALANINE]; SARAFOTOXIN S6C;

ADULT; AGED; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BLADDER NECK STENOSIS; CLINICAL ARTICLE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; PROTEIN LOCALIZATION; SMOOTH MUSCLE CONTRACTION;

AGED; AUTORADIOGRAPHY; HUMANS; MALE; MIDDLE AGED; MUSCLE CONTRACTION; RECEPTORS, ENDOTHELIN; URINARY BLADDER NECK OBSTRUCTION;

EID: 0035133773     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1159/000052412     Document Type: Article

References (23)

1. A potent vasoconstrictor peptide produced by vascular endothelial cells
2. Endothelin-1 in the human prostate: Tissue levels, source of production and isometric tension studies
3. Endothelin-1 production and decreased en-dothelin B receptor expression in advanced prostate cancer
4. Endothelin-1 production and agonist activities in cultured prostate-derived cells: Implications for regulation of endothelin bioactivity in prostatic hyperplasia
5. Cloning and expression of a cDNA encoding and endothelin receptor
6. Molecular characterisation of endothelin receptors
7. Binding and functional properties of endothelin receptor subtypes in the human prostate
8. Localisation of endothelin receptors in the human prostate
9. Gene expression and autoradiographic localisation of endothelin-1 and its receptors A and B in different zones of the normal prostate
10. Identification of endothelin receptors in normal and hyperplastic human prostatic tissues
11. Benign prostatic hypertrophy affects the endothelin receptor density in the human urinary bladder and prostate
12. Regional variation in the density and subtype specificity of denothelin receptors in rabbit urinary tract
13. Increased expression of endothelin-B receptors in the diabetic urinary bladder: Functional relevance
14. 125I]-PD151242: A selective radioligand for human ETA receptors
15. 1,3,11,15] in human heart
16. Increased expression of genes for basic fibroblast growth factor and transforming growth factor Type β2 in human benign prostatic hyperplasia
17. Mitogenic activity of endothelin on human cultured prostatic smooth muscle cells
18. Endothelin attenuates apoptosis in human smooth muscle cells
19. Release of endothe-lin from porcine aorta: Inhibition by endothelin-derived nitric oxide
20. Endothelin-1 as a putative modulator of erectile dysfunction. I. Characteristics of contraction of isolated corporal tissue strips
21. Potentiation of norepinephrine-induced contractions by endothelin-1 in the rabbit aorta
22. 1-adrenergic contractions is tissue specific in diverse rabbit vasculature
23. Endothelin: A new cardiovascular regulatory peptide