p53 mutation is infrequent in clear cell carcinoma of the ovary

Gynecologic Oncology

Volumn 80, Issue 2, 2001, Pages 189-193

  Shih Chu Ho, Esther ^a   Lai, Chiung Ru ^b   Hsieh, Yeun Ting ^a   Chen, Jung Ta ^a   Lin, Ai Jane ^a   Hung, Man Jung ^a   Liu, Fu Shing ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Clear cell carcinoma; Mutation; Ovary; p53

Indexed keywords

DNA; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DO 7; MONOCLONAL ANTIBODY PAB 1801; PROTEIN P53; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER STAGING; CARCINOGENESIS; CLEAR CELL CARCINOMA; CLINICAL ARTICLE; DNA DETERMINATION; DNA SEQUENCE; EXON; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MISSENSE MUTATION; MOLECULAR BIOLOGY; OVARY CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0035133750     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.2000.6025     Document Type: Article

References (30)

1. Surface epithelial-stromal tumors of the ovary
2. Clear cell carcinoma of the ovary: A study of 59 cases
3. Clear cell adenocarcinoma of the ovary: A clinical analysis and comparison with serous carcinoma
4. Ovarian clear cell adenocarcinoma
5. Clear cell carcinoma of the ovary: A distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy in stage III disease
6. Clinical characteristics of clear cell carcinoma of the ovary
7. Overexpression and mutation of p53 in epithelial ovarian cancer
8. Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer
9. p53 gene mutations and protein accumulation in human ovarian cancer
10. A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma
11. Immunohistochemical detection of mutant p53 protein in epithelial ovarian cancer using polyclonal antibody CMI: Correlation with histopathology and clinical features
12. Immunostaining of p53 protein in ovarian carcinoma: Correlation with histopathological data and clinical outcome
13. bcl-2 expression, p53 accumulation, and apoptosis in ovarian carcinomas
14. Prognostic significance of p53 immunostaining in epithelial ovarian cancer
15. p53 protein detected by immunohistochemistry as a prognostic factor in patients with epithelial ovarian carcinoma
16. Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma
17. Mutation and overexpression of p53 in early-stage epithelial ovarian cancer
18. P53 expression in ovarian borderline tumors and stage I carcinomas
19. Alteration of p53 gene in ovarian carcinoma: Clinicopathological correlation and prognostic significance
20. Alteration of p53 in ovarian cancer: Its occurrence and maintenance in tumor progression
21. Clear cell carcinoma has an expression pattern of cell cycle regulatory molecules that is unique among ovarian adenocarcinomas
22. p53 in tumor pathology: Can we trust immunohistochemistry? Revisited!
23. Frequent allelic losses and mutations of the p53 gene in human ovarian cancer
24. Exon 5 of the p53 gene is a target for deletions in ovarian cancer
25. p53 mutations in human cancers
26. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
27. Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53
28. The regulation of p53 function: Steiner Award lecture
29. Prevalence and significance of HER-2/neu expression in early epithelial ovarian cancer
30. TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumors and stage I carcinoma