Yersinia lead SUMO attack

Nature Medicine

Volumn 7, Issue 1, 2001, Pages 21-23

  Cornelis, G R ^a   Denecker, G ^a  

^a DE DUVE INSTITUTE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN YOPS; SUMO 1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN; UNCLASSIFIED DRUG;

APOPTOSIS; CELL PROLIFERATION; CYTOKINE PRODUCTION; CYTOSOL; ENZYME INHIBITION; INFLAMMATION; MACROPHAGE; NONHUMAN; PATHOGENESIS; PLAGUE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SHORT SURVEY; SIGNAL TRANSDUCTION; SPLEEN CELL; YERSINIA PESTIS;

ANIMALS; BACTERIAL PROTEINS; INFLAMMATION MEDIATORS; INTERFERON TYPE II; MICE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; YERSINIA; YERSINIA INFECTIONS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; YERSINIA; YERSINIA PESTIS;

EID: 0035132327     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/83298     Document Type: Short Survey

References (14)

1. Disruption of signaling by Yersinia Effector Yop J, a ubiquitin-like protein protease
2. Assembly and function of type III secretory systems
3. Association between virulence of Yersinia pestis and suppression of γ interferon and tumor necrosis factor α
4. Role of YopP in suppression of tumor necrosis factor α release by macrophages during Yersinia infection
5. The yopj locus is required for Yersinia-mediated inhibition of Nf-κB activation and cytokine expression: YopJ contains a eukaryotic SH2-like domain that is essential for its repressive activity
6. The bacterial protein YopJ abrogates multiple signal transduction pathways that converge on the transcription factor CREB
7. YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF-α production and downregulation of the MAP kinases p38 and JNK
8. Yersinia enterocolitica impairs activation of transcription factor NF-κB: Involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor alpha production
9. Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector
10. Recognition of the bacterial avirulence protein AvrBs3 occurs inside the host plant cell
11. Ubiquitin-like proteins: New wines in new bottles
12. YopJ of Yersinia spp is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cells
13. Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein
14. Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice