PCAP is the major known prostate cancer predisposing locus in families from South and West Europe

European Journal of Human Genetics

Volumn 9, Issue 2, 2001, Pages 135-142

  Cancel Tassin, Géraldine ^a   Latil, Alain ^a   Valéri, Antoine ^a,b   Mangin, Philippe ^c   Fournier, Georges ^b   Berthon, Philippe ^a   Cussenot, Olivier ^a,d,e  

^a Parc Scientifique de Luminy   (France)

^b SERVICE DE RHUMATOLOGIE   (France)

^c CHU NANCY BRABOIS   (France)

^d INSTITUT UNIVERSITAIRE DE FRANCE   (France)

^e SAINT LOUIS HOSPITAL   (France)

Author keywords

Genetic heterogeneity; Hereditary; Linkage analysis; PCaP (predisposing for cancer prostate); Prostate cancer

Indexed keywords

ADULT; AGE; AGED; ARTICLE; CANCER DIAGNOSIS; CHROMOSOME 1P; CHROMOSOME 1Q; CHROMOSOME XQ; CONTROLLED STUDY; FAMILIAL CANCER; FAMILY STUDY; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; GENETIC PARAMETERS; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; PEDIGREE; POPULATION; PRIORITY JOURNAL; PROSTATE CANCER; SOUTHERN EUROPE; WESTERN EUROPE;

EID: 0035131464     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200592     Document Type: Article

References (26)

1. Family history and the risk of prostate cancer
2. Mendelian inheritance of familial prostate cancer
3. Hereditary prostate cancer: Epidemiologic and clinical features
4. Segregation analysis of prostate cancer in Sweden: Support for dominant inheritance
5. Evidence for autosomal dominant inheritance of prostate cancer
6. Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search
7. Early age at diagnosis in families providing evidence of linkage to the hereditary prostate cancer locus (HPC1) on chromosome 1
8. Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25
9. Linkage analysis of chromosome 1q markers in 136 prostate cancer families
10. Predisposing gene for early-onset prostate cancer, localized on chromosome 1q42.2-43
11. Linkage analysis of 150 high-risk prostate cancer families at 1q24-25
12. Prostate cancer susceptibility locus on chromosome 1q: A confirmatory study
13. Prostate cancer susceptibility locus on chromosome 1q: A confirmatory study
14. Prostate cancer susceptibility locus HPC1 in Utah high-risk pedigrees
15. Combined analysis of hereditary prostate cancer linkage to 1q24-25: Results from 772 hereditary prostate cancer families from the international consortium for prostate cancer genetics
16. No evidence of linkage for chromosome 1q42.2-43 in prostate Cancer
17. Analysis of chromosome 1q42.2-43 in 152 families with high risk of prostate cancer
18. Linkage analyses at the chromosome 1 loci 1q24-25 (HPC1), 1q42.2-43 (PCAP), and 1p36 (CAPB) in families with hereditary prostate cancer
19. Evidence for a prostate cancer susceptibility locus on the X chromosome
20. Linkage analysis of 153 prostate cancer families over a 30-cM region containing the putative susceptibility locus HPCX
21. Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36
22. Strategies for multilocus linkage analysis in humans
23. Faster sequential genetic linkage computations
24. Parametric and nonparametric linkage analysis: A unified multipoint approach
25. Analysis of Human Genetic Linkage
26. In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer