Insight into mammalian selenocysteine insertion: Domain structure and ribosome binding properties of Sec insertion sequence binding protein 2

Molecular and Cellular Biology

Volumn 21, Issue 5, 2001, Pages 1491-1498

  Copeland, P R ^a   Stepanik, V A ^a   Driscoll, D M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; SELENOCYSTEINE;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; GENE INSERTION; GENETIC TRANSFECTION; MAMMAL CELL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RIBOSOME SUBUNIT; RNA TRANSLATION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

3' UNTRANSLATED REGIONS; AMINO ACID SEQUENCE; ANIMALS; CENTRIFUGATION, DENSITY GRADIENT; CODON, TERMINATOR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCEROL; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE TERMINATION FACTORS; POINT MUTATION; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; RIBOSOMES; RNA; RNA, RIBOSOMAL, 28S; RNA-BINDING PROTEINS; SELENOCYSTEINE; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR CELLS, CULTURED;

ANIMALIA; EUKARYOTA; MAMMALIA; PROKARYOTA;

EID: 0035131148     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.5.1491-1498.2001     Document Type: Article

References (22)

1. Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3′ untranslated region
2. Biosynthesis of selenoproteins - An overview
3. Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp)
4. Tissue-specific functions of individual glutathione peroxidases
5. Purification, redox sensitivity, and RNA binding properties of SECIS-binding protein 2, a protein involved in selenoprotein biosynthesis
6. A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs
7. Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation
8. Potysome distribution of phospholipid hydroperoxide glutatione peroxidase mRNA: Evidence for a block in elongation at the UGA/selenocysteine codon
9. Selenocysteine-containing proteins in mammals
10. Control of translation initiation in animals
11. Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia
12. A novel RNA-binding motif in omnipotent suppressors of translation termination, ribosomal proteins and a ribosome modification enzyme?
13. Identification of a selenocysteyl-tRNA (Ser) in mammalian cells that recognizes the nonsense codon, UGA
14. An RNA-binding protein recognizes a mammalian selenocysteine insertion sequence element required for cotranslational incorporation of selenocysteine
15. A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex
16. Assays for eukaryotic protein synthesis
17. Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA
18. Starting at the beginning, middle, and end: Translation initiation in eukaryotes
19. The crystal structure of human eukaryotic release factor eRF1 - Mechanism of stop codon recognition and peptidyl-tRNA hydrolysis
20. Selenium biochemistry. Mammalian selenoenzymes
21. Decoding apparatus for eukaryotic selenocysteine insertion
22. Multiple functions of an evolutionarily conserved RNA binding domain