Calcium responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and somatostatin in phospholipase Cβ3 knockout mice

Molecular Endocrinology

Volumn 15, Issue 1, 2001, Pages 125-135

  Romoser, Valerie A ^a   Graves, Thomas K ^a   Wu, Dianqing ^a   Jiang, Huiping ^a   Hinkle, Patricia M ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; GONADORELIN; ISOPROTEIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA2; PHOSPHOLIPASE C BETA3; PHOSPHOLIPASE C BETA4; PROTIRELIN; SOMATOSTATIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SUBUNIT; HORMONAL REGULATION; HYPOPHYSIS CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA; BLOTTING, WESTERN; CALCIUM; CELLS, CULTURED; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GONADOTROPIN-RELEASING HORMONE; ISOENZYMES; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MUSCLE, SMOOTH, VASCULAR; PHOSPHOLIPASE C; PITUITARY GLAND; SIGNAL TRANSDUCTION; SOMATOSTATIN; THYROTROPIN-RELEASING HORMONE;

ANIMALIA;

EID: 0035130836     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.15.1.125     Document Type: Article

References (52)

1. Regulation of phosphoinositide-specific phospholipase C isozymes
2. Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex
3. Regulation of purified subtypes of phosphatidylinositol-specific phospholipase Cβ by G protein α and β γ subunits
4. Regulation of phospholipase C-β4 by ribonucleotides and the α subunit of Gq
5. Activation of phospholipase Cβ4 by heterotrimeric GTP-binding proteins
6. Cloning, sequencing, purification, and Gq-dependent activation of phospholipase C-β 3
7. Activation of phospholipase C isozymes by G protein βγ subunits
8. Phosphoinositide-specific phospholipase C and mitogenic signaling
9. Activation of phosphatidylinositol lipid-specific phospholipase C-β3 by G-protein βγ subunits
10. Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits
11. Activation of phospholipase Cβ2 by the α and βγ subunits of trimeric GTP-binding protein
12. Regulation of effectors by G-protein α- and β γ-subunits. Recent insights from studies of the phospholipase c-β isoenzymes
13. Characterization of the calcium response to thyrotropin-releasing hormone in lactotrophs and GH cells
14. Signaling mechanisms during the response of pituitary gonadotropes to GnRH
15. Calcium oscillations in anterior pituitary cells
16. + and Ca2+ conductances
17. Somatostatin and its receptor family
18. Somatostatin receptors present knowledge and future directions
19. + conductance in freshly dispersed rat somatotrophs
20. The elucidation of somatostatin receptor functions: A current view
21. Somatostatin receptor-mediated signaling in smooth muscle. Activation of phospholipase C-β3 by Gβγ and inhibition of adenylyl cyclase by Gαi1 and Gαo
22. Genetic alteration of phospholipase C β3 expression modulates behavioral and cellular responses to mu opioids
23. Adenosine A1 receptor-mediated activation of phospholipase C-β3 in intestinal muscle: Dual requirement for α and β γ subunits of Gi3
24. Mechanisms involved in the somatostatin-induced contraction of vascular smooth muscle cells
25. Low concentrations of dopamine increase cytosolic calcium in lactotrophs
26. Direct effect of adenosine on prolactin secretion at the level of the single rat lactotroph: Involvement of pertussis toxin-sensitive and -insensitive transducing mechanisms
27. Interference of endogenous B endorphin with opiate binding in the anterior pituitary
28. Phospholipase Cβ4 is involved in modulating the visual response in mice
29. Localization of mRNAs for three novel members (β 3, β4 and γ2) of phospholipase C family in mature rat brain
30. Ulcerative colitis and adenocarcinoma of the colon in Gαi2-deficient mice
31. Posttranslational modification of Gαo1 generates Gαo3, an abundant G protein in brain
32. Expression of the genes encoding bombesin-related peptides and their receptors in anterior pituitary tissue
33. Thyrotropin-releasing hormone and gonadotropin-releasing hormone receptors activate phospholipase C by coupling to the guanosine triphosphate-binding proteins Gq and G11
34. Selective reconstitution of gastrin-releasing peptide receptor with Gαq
35. Association of solubilized bradykinin B2 receptors with G-proteins
36. Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney
37. Phospholipase C activation and Ca2+ mobilization by cloned human somatostatin receptor subtypes 1-5, in transfected COS-7 cells
38. Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
39. Function and regulation of somatostatin receptor sub-types
40. Expression of mRNA for somatostatin receptor (sstr) types 2 and 5 in individual rat pituitary cells. A double labeling in situ hybridization analysis
41. Both overlapping and distinct signaling pathways for somatostatin receptor subtypes SSTR1 and SSTR2 in pituitary cells
42. Somatostatin (SSTR2) receptors mediate phospholipase C-independent Ca2+ mobilization in rat AR42J pancreas cells
43. Effect of somatostatin on resistance and on capacitance rabbit isolated arteries
44. Cell specific expression of the sst2A and sst5 somatostatin receptors in the rat anterior pituitary
45. Agonist-dependent interaction of the rat somatostatin receptor subtype 2 with cortactin-binding protein 1
46. Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain
47. Thyrotropin-releasing hormone-induced intracellular calcium responses in individual rat lactotrophs and thyrotrophs
48. Roles of PLC-β2 and -β3 and PI3Kγ, in chemoattractant-mediated signal transduction
49. Phospholipase C isozymes selectively couple to specific neurotransmitter receptors
50. Role of phospholipase Cβ3 phosphorylation in the desensitization of cellular responses to platelet-activating factor
51. Characteristics of the Ca2+ spike and oscillations induced by different doses of thyrotropin-releasing hormone (TRH) in individual pituitary cells and nonexcitable cells transfected with TRH receptor complementary deoxyribonucleic acid
52. Visualization of the thyrotropinreleasing hormone receptor and its ligand during endocytosis and recycling