Mutations in the hepatocyte nuclear factor-1β (MODY5) gene are not a major factor contributing to end-stage renal disease in Japanese people with diabetes mellitus

Diabetologia

Volumn 44, Issue 1, 2001, Pages 127-128

  Iwasaki, N ^a   Babazono, T ^a   Tomonaga, O ^a   Ogata, M ^a   Yokokawa, H ^a   Iwamoto, Y ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR I;

ADULT; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DISEASE DURATION; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; HUMAN; JAPAN; KIDNEY FAILURE; LETTER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR;

DIABETES MELLITUS, TYPE 2; DIABETIC NEUROPATHIES; DNA-BINDING PROTEINS; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; JAPAN; KIDNEY FAILURE, CHRONIC; MUTATION; TRANSCRIPTION FACTORS;

EID: 0035130265     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051590     Document Type: Letter

References (7)

1. Mutation in hepatocyte nuclear factor-1β gene (TCF2) associated with maturity-onset diabetes of the young
2. Frameshift mutation, A263fsinsGG, in the hepatocyte nuclear factor-1β gene associated with diabetes and renal dysfunction
3. A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1β
4. Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1β
5. Loss-of-function and dominant-negative mechanisms associated with hepatocyte factor-1β mutations in familial Type II diabetes mellitus
6. The mutated human gene encoding hepatocyte nuclear factor-1β inhibits kidney formation in developing Xenopus embryos
7. Hepatocyte nuclear factor-1β (MODY5) gene mutations in Scandinavian families with early-onset diabetes or kidney disease or both