Automated genotyping for accurate assignment of the (AT)xNz(AT)y motif within the β-globin locus control region-hypersensitive site 2

British Journal of Haematology

Volumn 112, Issue 2, 2001, Pages 488-492

  Tatu, Thanusak ^a   Thein, Swee Lay ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

LCR HS2; (AT)xNz(AT)y genotype; HbF

Indexed keywords

BETA GLOBIN;

ACCURACY; ARTICLE; AUTOMATION; CLINICAL ARTICLE; DINUCLEOTIDE REPEAT; DNA SEQUENCE; GENE AMPLIFICATION; GENE CONTROL; GENE LOCUS; GENOTYPE; HUMAN; PRIORITY JOURNAL; TANDEM REPEAT;

ALLELES; ANEMIA, SICKLE CELL; AUTOMATIC DATA PROCESSING; GENOTYPE; GLOBINS; HUMANS; MOLECULAR CONFORMATION; SEQUENCE ANALYSIS, DNA; TANDEM REPEAT SEQUENCES;

EID: 0035129977     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02539.x     Document Type: Article

References (12)

1. Aγ enhancer
2. Aγ expression in adults
3. Cγ globin production
4. S chromosomes with five different haptotypes
5. Fetal hemoglobin in sickle cell anemia: Relation to regulatory sequences cis to the β-globin gene
6. Variation of fetal hemoglobin and F-cell number with the LCR-HS2 polymorphism in nonanemic individuals
7. S chromosomes are associated with different levels of fetal globin in hemoglobin S homozygotes
8. A potential regulatory region for the expression of fetal hemoglobin in sickle cell disease
9. Chromosome-specific microsatellite sets for fluorescence-based, semi-automated genome mapping
10. Variation of HbF and F-cell number with the G-γ Xmn I (C-T) polymorphism in normal individuals
11. Detailed analysis of the site 3 region of the human β-globin dominant control region
12. S haplotypes are generated by diverse genetic mechanisms