Approach to a multiparametric sensor-chip-based tumor chemosensitivity assay

Anti-Cancer Drugs

Volumn 12, Issue 1, 2001, Pages 21-32

  Henning, T ^a   Brischwein, M ^a   Baumann, W ^a   Ehret, R ^a   Freund, I ^a   Kammerer, R ^a   Lehmann, M ^a   Schwinde, A ^a   Wolf, B ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cell adhesion; Cell metabolism; Chemosensitivity assay; Sensor chip; Tumor tissue culture

Indexed keywords

SILICON;

ACIDIFICATION; ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL METABOLISM; CELL RESPIRATION; CELL STRUCTURE; CHEMOSENSITIVITY; CYTOTOXICITY; DRUG DETERMINATION; IMPEDANCE; MITOCHONDRION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SENSOR; TREATMENT PLANNING;

ACETALDEHYDE; ANTIBIOTICS, ANTINEOPLASTIC; BIOSENSING TECHNIQUES; BREAST NEOPLASMS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; LUNG NEOPLASMS; MITOCHONDRIA; OXYGEN; TUMOR CELLS, CULTURED;

EID: 0035128816     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200101000-00004     Document Type: Article

References (30)

1. Use of an ex vivo ATP luminescence assay to direct chemotherapy for recurrent ovarian cancer
2. The Cytosensor microphysiometer: Biological applications of silicon technology
3. Microphysiometry: New technology for evaluation of anticancer drug activity in human tumor cells in vitro
4. Comparison of the tetrazolium salt assay for succinate dehydrogenase with the Cytosensor microphysiometer in the assessment of compound toxicities
5. Biosensorik mit zellulären Systemen
6. Monitoring of cellular signalling and metabolism with modular sensor-technique: The PhysioControl-Microsystem (PCM)
7. Approach to multiparametric biochips for cell-based screening
8. Monitoring of cellular behaviour by impedance measurements on interdigitated electrode structures
9. Microelectronic sensor system for microphysiological application on living cells
10. Biosensors based on the energy metabolism of living cells: The physical chemistry and cell biology of extracellular acidification
11. Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration
12. Ifosfamide stereoselective dichloroethylation and neurotoxicity
13. Overall tracer studies with C14-labeled nitrogen mustard in normal and leukemic mice
14. Ultrastructural localization of carcinoembryonic antigen in a continuous human tumor cell line (LS 174 T) in relation to morphometric investigations
15. Resistance mechanisms in murine tumors with acquired multidrug resistance
16. Ifosfamide and mesna: Effects on the Na/H exchanger activity in renal epithelial cells in culture (LLC-PK1)
17. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
18. Does cancer therapy trigger cell suicide?
19. Primary bioassay of human tumor stem cells
20. Quantitation of differential sensitivity of human-tumor stem cells to anticancer drugs
21. The interaction of adriamycin with cardiolipin in model and rat liver mitochondrial membranes
22. A new class of free radical scavengers reducing adriamycin mitochondrial toxicity
23. Criteria for assessing normal and abnormal mitochondrial function
24. Flow cytometric measurement of mitochondrial mass and function: A novel method for assessing chemoresistance
25. Adhesion systems in normal breast and in invasive breast carcinoma
26. Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis
27. Fibroblast growth factors: An epigenetic mechanism of broad spectrum resistance to anticancer drugs
28. Implications of acidic tumor micro-environment for neoplastic growth and cancer treatment: A computer analysis
29. The potential role of transformation-induced metabolic changes in tumor-host interaction