Pharmacological and clinical properties of beraprost sodium, orally active prostacyclin analogue

Folia Pharmacologica Japonica

Volumn 117, Issue 2, 2001, Pages 123-130

  Nishio, S ^a   Kurumatani, H ^a  

^a TORAY INDUSTRIES INC   (Japan)

Author keywords

Beraprost sodium; Chronic arterial occlusion; Dorner ; Primary pulmonary hypertension; Procylin

Indexed keywords

BERAPROST; PROSTACYCLIN DERIVATIVE;

DRUG EFFECT; DRUG USE; HUMAN; INTERMITTENT CLAUDICATION; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PULMONARY HYPERTENSION; REVIEW; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; VASCULAR ENDOTHELIUM;

ADMINISTRATION, ORAL; ANIMALS; ARTERIAL OCCLUSIVE DISEASES; CHRONIC DISEASE; CLINICAL TRIALS; EPOPROSTENOL; HUMANS; HYPERTENSION, PULMONARY; PLATELET AGGREGATION INHIBITORS; VASODILATOR AGENTS;

EID: 0035128302     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.117.123     Document Type: Review

References (47)

1. An enzyme isolated from arteries transforms prostaglandin endoperoxidases to an unstable substance that inhibits platelet aggregation
2. Biological importance of prostacyclin
3. 2 derivatives and their inhibitory activities to human platelet aggregation
4. The in vitro and ex vivo antiplatelet effect of TRK-100, a stable prostacyclin analog, in several species
5. Inhibitory effect of beraprost on platelet aggregation: Comparative study utilizing two methods of aggregometry
6. 2 analogue
7. Effect of beraprost sodium on peripheral circulatory disturbances induced by various stimuli
8. Evaluation of microangiopathy of the skin in patients with noninsulin-dependent diabetes mellitus by laser Doppler flowmetry; microvasodilatory responces to beraprost sodium
9. Cytoprotective action of beraprost sodium against peroxideinduced damage in vascular endothelial cells
10. Cytoprotective effect of TRK-100, a prostacyclin analogue, against chemical injuries in cultured human vascular endothelial cells
11. Specific binding of new stable epoprostenol analogue beraprost sodium to prostacyclin receptors on human and rat platelets
12. Pharmacokinetics and platelet antiaggregation of beraprost, an oral stable prostacyclin analogue, in healthy volunteers
13. A dose-effect study of beraprost sodium in intermittent claudication
14. 2 analogue, for intermittent claudication: A double-blind randomized multicenter controlled trial
15. Primary pulmonary hypertension
16. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
17. Orally active prostacyclin analogue in primary pulmonary hypertension
18. Effect of orally active prostacyclin analogue on survival of outpatients with primary pulmonary hypertension
19. 2 analogue) in the atherosclerotic rabbit artery after angioplasty
20. The effect of beraprost Na, a stable prostacyclin analog, on animal model of stroke
21. Effect of beraprost sodium and insulin on the electroretinogram, nerve conduction, and nerve blood flow in rat with streptozotocin-induced diabetes
22. Therapeutic effects of prostacyclin analog on crescentic glomerulonephritis of rat
23. 2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition