Is random screening of value in detecting glucocorticoid-remediable aldosteronism within a hypertensive population?

Journal of Human Hypertension

Volumn 15, Issue 3, 2001, Pages 173-176

  Gates, L J ^a   Benjamin, N ^b   Haites, N E ^a   MacConnachie, A A ^a   McLay, J S ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Cerebral haemorrhage; Glucocorticoid remedial alodosteronism; Hypokalaemia; Screening

Indexed keywords

ALDOSTERONE SYNTHASE; AMILORIDE; AMLODIPINE; ANTIHYPERTENSIVE AGENT; ATENOLOL; BENDROFLUMETHIAZIDE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DEXAMETHASONE; ENALAPRIL; GLUCOCORTICOID; SPIRONOLACTONE; STEROID 11BETA MONOOXYGENASE; THIAZIDE DIURETIC AGENT;

ADOLESCENT; ADULT; ARTICLE; BRAIN HEMORRHAGE; CHIMERA; CLINICAL TRIAL; DIAGNOSTIC VALUE; DISEASE SEVERITY; ESSENTIAL HYPERTENSION; FAMILY HISTORY; FEMALE; GENE MUTATION; HIGH RISK POPULATION; HUMAN; HYPERALDOSTERONISM; HYPERTENSION; HYPOKALEMIA; INHERITANCE; MAJOR CLINICAL STUDY; MALE; MASS SCREENING; MORBIDITY; MORTALITY; PROSPECTIVE STUDY;

EID: 0035127446     PISSN: 09509240     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jhh.1001152     Document Type: Article

References (15)

1. Genetics and the nature of essential hypertension
2. The aetiology of essential hypertension. 4. The role of inheritance
3. Autosomal dominant transmission and absence of HLA linkage in dexamethasone suppressible hyperaldosteronism
4. Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone
5. A new form of congenital adrenal hyperplasia
6. A case of glucocorticoid-responsive aldosteronism
7. A kindred with familial glucocorticoid-suppressible aldosteronism
8. Genetic and pathophysiologic studies of a new kindred with glucocorticoid-suppressible hyperaldosteronism manifest in three generations
9. Chimaeric 11β-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
10. Characterisation of two genes encoding human steroid 11β-hydroxylase (P-450 11β)
11. Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotrophin-dependant and mediates hypertension in dexamethasone-suppressible aldosteronism
12. Amiloride in the treatment of primary hyperaldosteronism and essential hypertension
13. Long term evaluation of glucocorticoid-suppressible hyperaldosteronism
14. Variation of phenotype in patients with glucocorticoid remediable aldosteronism
15. Intracranial aneurysm and haemorrhagic stroke in glucocorticoid-remedial aldosteronism