Effects of inhaled prostacyclin analogue on chronic hypoxic pulmonary hypertension

Journal of Cardiovascular Pharmacology

Volumn 37, Issue 3, 2001, Pages 239-251

  Abe, Yuzo ^a   Tatsumi, Koichiro ^a   Sugito, Kazutoshi ^a   Ikeda, Yuji ^a   Kimura, Hiroshi ^a   Kuriyama, Takayuki ^a  

^a CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hypoxic pulmonary vasoconstriction; Prostacyclin; Prostacyclin receptor

Indexed keywords

BERAPROST; MESSENGER RNA; PROSTACYCLIN DERIVATIVE; PROSTACYCLIN RECEPTOR;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CHRONIC DISEASE; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; GENE EXPRESSION; HYPOXIA; LUNG VASCULAR RESISTANCE; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; VASODILATATION;

ADMINISTRATION, INHALATION; ANIMALS; ANOXIA; CHRONIC DISEASE; EPOPROSTENOL; HEMODYNAMIC PROCESSES; HYPERTENSION, PULMONARY; INJECTIONS, INTRAVENOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, EPOPROSTENOL; RECEPTORS, PROSTAGLANDIN; RNA, MESSENGER;

EID: 0035127428     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200103000-00002     Document Type: Article

References (32)

1. 2
2. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
3. 2) on hypoxic pulmonary vasoconstriction in the conscious adult sheep
4. ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog
5. Influence of adenosine and prostacyclin on hypoxia-induced pulmonary hypertension in the anaesthetized pig
6. Reduction in pulmonary vascular resistance with long-term Epoprostenol (prostacyclin) therapy in primary pulmonary hypertension
7. Prostacyclin aerosol in an infant with pulmonary hypertension
8. Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome
9. 2 aerosol versus nitric oxide for selective pulmonary vasodilation in hypoxic pulmonary vasoconstriction
10. Effects of inhaled prostacyclin as compared with inhaled nitric oxide on right ventricular performance in hypoxic pulmonary vasoconstriction
11. Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis
12. Combined inhaled nitric oxide and inhaled prostacyclin during experimental chronic pulmonary hypertension
13. Effects of inhaled versus intravenous vasodilators in experimental pulmonary hypertension
14. Effects of inhaled nitric oxide and nebulized prostacyclin on hypoxic pulmonary vasoconstriction in anesthetized sheep
15. Orally active prostacyclin analogue in primary pulmonary hypertension
16. 2, from isolated rat lung during vasoconstriction
17. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension
18. Rat pulmonary circulation after chronic hypoxia: Hemodynamic and structural features
19. An ultrasonic pulsed Doppler system for measuring blood flow in small vessels
20. High frequency pulsed Doppler measurements of blood flow and myocardial dimensions in conscious animals
21. Role of carotid body in pressure response of pulmonary circulation in rats
22. Cloning and expression of a cDNA for rat prostacyclin receptor
23. 1, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension
24. Pressurized aerosol versus jet aerosol delivery to mechanically ventilated patients - Comparison of dose to the lungs
25. Lung metabolism of eicosanoids: Prostaglandins, prostacyclin, thromboxane, and leukotrienes
26. Prostacyclin-sensitive adenylate cyclase and prostacyclin binding sites in platelets and smooth muscle cells
27. Pulmonary microvascular responses to inhaled prostacyclin, nitric oxide, and their combination in anesthetized cats
28. Lungs from chronically hypoxic rats have decreased pressor response to acute hypoxia
29. Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat
30. 2 and PGI analogues on cAMP levels in cultured endothelial and smooth muscle cells derived from bovine arteries
31. 2 analogue, on reperfusion injury to rabbit lungs
32. Adaptation of pharmacomechanical coupling of vascular smooth muscle to chronic hypoxia