Alkylxanthine-induced recovery of respiratory function following cervical spinal cord injury in adult rats

Experimental Neurology

Volumn 168, Issue 1, 2001, Pages 123-134

  Nantwi, Kwaku D ^a   Goshgarian, Harry G ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine receptors; Alkylxanthines; Cervical spinal cord injury; Functional recovery; Paralysis; Respiration

Indexed keywords

8 (4 SULFOPHENYL)THEOPHYLLINE; 8 PHENYLTHEOPHYLLINE; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ENPROFYLLINE; PANCURONIUM; THEOPHYLLINE DERIVATIVE; XANTHINE DERIVATIVE;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CERVICAL SPINAL CORD INJURY; CONTROLLED STUDY; CONVALESCENCE; DIAPHRAGM PARALYSIS; DRUG INDUCED DISEASE; DRUG MECHANISM; FEMALE; NERVE CONDUCTION; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RAT; RESPIRATORY FUNCTION;

EID: 0035126856     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7581     Document Type: Article

References (54)

1. Effects of quizodine on phosphodiesterase (35357)
2. Noninvasive options for ventilatory support of the traumatic high level quadriplegic patient
3. Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding
4. Phosphodiesterase inhibition and theophylline
5. Enprofylline kinetics in healthy subjects after single doses
6. Effect of the adenosine antagonist 8-phenyltheophylline on glycerol-induced acute renal failure in the rat
7. Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts
8. Changes in the phrenic nerve, hypoglossal and recurrent laryngeal nerve activities after intravenous infusions of aminophylline in cats
9. Evidence that the positive inotropic effects of alkylxanthines are not due to adenosine receptor blockade
10. The adenosine receptor antagonist, 8-phenyltheophylline, causes diuresis and saliuresis in the rat
11. Receptors for adenine nucleotides and nucleosides: Subclassification, distribution and molecular characterization
12. 1 receptors
13. Quantitative assessment of respiratory function following contusion injury of the spinal cord
14. Antagonism by theophylline of respiratory inhibition induced by adenosine
15. Mechanism of respiratory effects of methylxanthines
16. Studies on the motor cells of the spinal cord. 1. Distribution in the normal human cord
17. Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-Sulfophenyl)theophylline
18. Clinical effects of theophylline on inspiratory muscle drive in tetraplegia
19. Xanthine derivatives as adenosine receptor antagonists
20. Developmental plasticity in the respiratory pathway of the adult rat
21. Demonstration of functionally ineffective synapses in the guinea pig spinal cord
22. Effect of cervical spinal cord hemisection and diaphragm paralysis on arterial blood gases, Ph and respiratory rate in the adult rat
23. The ultrastructure and synaptic architecture of phrenic motor neurons in the spinal cord of the adult rat
24. The phrenic nucleus of the albino rat: A correlative HRP and Golgi study
25. 1-purinergic antagonist
26. Stimulation of endogenous catecholamine release by theophylline: A proposed additional mechanism of action for theophylline effects
27. Adenosine receptors: Pharmacology, structure-activity relationships, and therapeutic potential
28. Relationship of plasma and brain concentrations of caffeine and metabolites to benzodiazepine receptor binding and locomotor activity
29. Organization of the phrenic nucleus in the spinal cord of the cat and man
30. Significance of the crossed phrenic phenomenon
31. Quantitative assessment of the effect of chronic phrenicotomy on the induction of the crossed phrenic phenomenon
32. Identification of axon pathways which mediate functional recovery of a paralyzed hemidiaphragm following spinal cord hemisection in the adult rat
33. Spontaneous functional recovery in a paralyzed hemidiaphragm following spinal cord injury in adult rats
34. Actions of systemic theophylline on hemidiaphragmatic recovery in rats following cervical spinal cord hemisection
35. Effects of chronic systemic theophylline injections on recovery of hemidiaphragmatic function after cervical spinal cord injury in adult rats
36. Theophylline-induced recovery in a hemidiaphragm paralyzed by hemisection in rats. Contribution of adenosine receptors
37. 2-selective adenosine agonists and antagonists: Evidence for synergism and antagonism
38. Adenosine receptor sub-types: Characterization and therapeutic regulation
39. Quantitative assessment of phrenic nerve functional recovery mediated by the crossed phrenic reflex at various time intervals after spinal cord injury
40. Effects of enprofylline and theophylline may show the role of adenosine
41. Drugs used in treatment of asthma. The methylxanthines, cromolyn sodium, and other agents
42. Action of caffeine and aminophylline as respiratory stimulants in man
43. Ventilatory function in cervical and high thoracic spinal cord injury
44. New derivatives of methyl-xanthines: Effect of thiocaffeine, thiotheophylline and 8-phenyltheophylline on lipolysis and phosphodiesterase activities
45. Alkylxanthines: Inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity
46. Home positive-pressure ventilation twenty years' experience
47. Effects of caffeine and theophylline on activity of rats in relation to brain xanthine concentrations
48. Differentiation of the peripherally mediated from the centrally mediated influences of adenosine in the rat during systemic hypoxia
49. Phrenicotomie et examen anatomique de la moelle cervicale
50. Cerebral schema in gerbils: Postischemic administration of cyclohexyladenosine and 8-sulfophenyl-theophylline
51. Theophylline prescribing, serum concentrations, and toxicity
52. Pharmacokinetics of 8-phenyltheophylline in the rat
53. Effects of adenosine receptor agents on the expression of morphine withdrawal in mice