Cytochrome P450 drug interactions: Are they clinically relevant?

Australian Prescriber

Volumn 24, Issue 1, 2001, Pages 10-12

  Martin, J ^a   Fay, M ^a  

^a Clinical Pharmacology Unit   (Australia)

Author keywords

Drug metabolism; Pharmacokinetics; Warfarin

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIINFECTIVE AGENT; CARBAMAZEPINE; CARDIOVASCULAR AGENT; CYCLOSPORIN; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; CYTOCHROME P450 ISOENZYME; DILTIAZEM; ENZYME INDUCING AGENT; ERYTHROMYCIN; FELODIPINE; FLUCONAZOLE; IMMUNOSUPPRESSIVE AGENT; INDINAVIR; ITRACONAZOLE; KETOCONAZOLE; MICONAZOLE; ORAL CONTRACEPTIVE AGENT; OXCARBAZEPINE; PHENYTOIN; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; SILDENAFIL; TACROLIMUS; UNINDEXED DRUG; WARFARIN;

CONCENTRATION RESPONSE; DRUG BIOAVAILABILITY; DRUG METABOLISM; ENZYME INDUCTION; ENZYME INHIBITION; FIRST PASS EFFECT; FOOD DRUG INTERACTION; FRUIT JUICE; HUMAN; HYPERICUM PERFORATUM; PROTEIN FAMILY; REVIEW;

EID: 0035126640     PISSN: 03128008     EISSN: None     Source Type: Journal    
DOI: 10.18773/austprescr.2001.007     Document Type: Review

References (10)

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8. Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics of felodipine - And its potential clinical relevance
9. The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: Implications for drug interactions
10. SNaRIs, NaSSAs, and NaRIs: New agents for the treatment of depression