The effects on hypercarbic ventilatory response of Sameridine compared to morphine and placebo

Anesthesia and Analgesia

Volumn 92, Issue 2, 2001, Pages 529-534

  Österlund, Modalen ^a   Arlander, Eva ^a   I Eriksson, Lars ^a   G E Lindahl, Sten ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

LOCAL ANESTHETIC AGENT; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; PLACEBO; SAMERIDINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CAPNOGRAPHY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG INFUSION; FEMALE; HUMAN; HYPERCAPNIA; LOCAL ANESTHESIA; LUNG VENTILATION; MALE; NORMAL HUMAN; PNEUMOTACHYGRAPHY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEDATION; SINGLE BLIND PROCEDURE; STEADY STATE;

EID: 0035126153     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200102000-00046     Document Type: Article

References (12)

1. Respiratory depression and spinal opioids: Review article
2. The effect of local anesthetics on the central circulation and respiration in man and dog
3. Influence of local anesthetics on ventilation
4. The local anaesthetic sameridine is a selective ligand and a partial agonist at cloned human mu-receptors
5. Intrathecal administration of sameridine to patients subjected to arthroscopic knee joint surgery
6. Effects on resting ventilation of intravenous infusions of morphine or sameridine, a novel molecule with both local anesthetic and opioid properties
7. Ventilatory sensitivity to CO2 after IV lidocaine
8. The effect of lidocaine infusion on the ventilatory response to carbon dioxide
9. Ventilatory response to CO2 following intravenous and epidural lidocaine
10. The effect of lidocaine on the ventilatory response to hypoxia
11. Differential roles of opioid receptors in respiration, respiratory disease, and opiate-induced respiratory depression: State of the art
12. The effects of drugs on respiration in man