Short- and long-term functional alterations of the skeletal muscle calcium release channel (Ryanodine receptor) by suramin: Apparent dissociation of single channel current recording and [3H]ryanodine binding

Molecular Pharmacology

Volumn 59, Issue 3, 2001, Pages 543-556

  Suko, Josef ^a   Hellmann, Gertrude ^a   Drobny, Helmut ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CALMODULIN; MAGNESIUM ION; RYANODINE; RYANODINE RECEPTOR; SURAMIN; THIOL DERIVATIVE; TRITIUM;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; CALCIUM BINDING; CHANNEL GATING; CONTROLLED STUDY; DISSOCIATION; DRUG RECEPTOR BINDING; LIGAND BINDING; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RABBIT; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE;

EID: 0035126109     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.3.543     Document Type: Article

References (36)

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3. Planar bilayer recordings of ryanodine receptors of sarcoplasmic reticulum
4. Structure and function of ryanodine receptors
5. Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes
6. Calcium-dependent block of ryanodine receptor channel of swine skeletal muscle by direct binding of calmodulin
7. 3H]ryanodine binding
8. Cations and anions as modifiers of ryanodine binding to the skeletal muscle calcium release channel
9. Activation of skeletal muscle ryanodine receptor by suramin and suramin analogs
10. Pharmacological activation of the ryanodine receptor in Jurkat T-Lymphocytes
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12. Purification of the ryanodine receptor and its identity with the feet structures of junctional terminal sarcoplasmic reticulum from fast skeletal muscle
13. Determination of microgram quantities of protein in the presence of milligram levels of lipid with amido black 10B
14. Calmodulin
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20. 2+ and monovalent cations and anions
21. 2+ ions in excitation-contraction coupling of skeletal muscle fibers
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23. 2+ caffeine, and adenine nucleotides
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26. Purified ryanodine receptor from rabbit skeletal muscle is the calcium release channel of sarcoplasmic reticulum
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29. 3H]ryanodine binding
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