The calcium inhibitor SR33805 reduces intimal formation following injury of the porcine carotid artery

Atherosclerosis

Volumn 154, Issue 2, 2001, Pages 301-308

  Hainaud, Patricia ^a   Bonneau, Michel ^b   Pignaud, Georges ^c   Sollier, Claire Bal dit ^a   André, Patrick ^c   Hadjiisky, Peter ^e   Fieffé, Jean Paul ^a   Caen, Jacques P ^a   Herbert, Jean Marc ^d   Dol, Frédérique ^d   Drouet, Ludovic O ^a,c  

^a HÔPITAL LARIBOISIÈRE   (France)

^b CEMAGREF   (France)

^c SAINT LOUIS HOSPITAL   (France)

^d SANOFI   (France)

^e Service de Bactériologie   (France)

Author keywords

Animal model; Calcium channel antagonist; Intimal proliferation; Porcine carotid artery; Smooth muscle cells migration

Indexed keywords

2 [4 [3 [N (3,4 DIMETHOXYPHENETHYL) N METHYLAMINO]PROPOXY]BENZENESULFONYL] 3 ISOPROPYL 1 METHYLINDOLE; BASIC FIBROBLAST GROWTH FACTOR; CALCIUM CHANNEL BLOCKING AGENT; PLATELET DERIVED GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY BLOOD FLOW; ARTERY DIAMETER; ARTERY INTIMA PROLIFERATION; ARTICLE; CAROTID ARTERY INJURY; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FETAL CALF SERUM; IC 50; IN VITRO STUDY; IN VIVO STUDY; LONG TERM CARE; MALE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; SWINE;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; CALCIUM CHANNEL BLOCKERS; CAROTID ARTERY INJURIES; CAROTID ARTERY, COMMON; CELL COUNT; CELL DIVISION; INDOLES; MALE; MICROSCOPY, VIDEO; MUSCLE, SMOOTH, VASCULAR; SULFONES; SWINE; TUNICA INTIMA;

EID: 0035125376     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(00)00487-1     Document Type: Article

References (56)

1. The pathogenesis of atherosclerosis - An update
2. Inhibitory effect of calcium antagonists on balloon catheter-induced arterial smooth muscle cell proliferation and lesion size
3. A review of calcium antagonists and atherosclerosis
4. Comparison of nifedipine, propranonol and isosorbide-dinitrate on angiographic progression and regression of coronary arterial narrowings in angina pectoris
5. Retardation of angiographic progression of coronary artery disease by nifedipine: Results of the international nifedipine trial on antiatherosclerotic therapy (INTACT)
6. Calcium channel blockers and atherogenesis
7. The antiatherogenic potential of calcium antagonists
8. Calcium antagonists and ACAT inhibitors promote cholesterol efflux from macrophages by different mechanisms: II: Characterization of cellular lipid metabolism
9. Calcium antagonists and ACAT inhibitors promote cholesterol efflux from macrophages by different mechanisms: II: Characterization of intracellular morphologic changes
10. Verapamil enhances receptor-mediated endocytosis of low density lipoproteins by aortic cells in culture
11. Effect of verapamil on cholesteryl ester hydrolysis and reesterification in macrophages
12. The calcium antagonist nifedipine inhibits arterial smooth muscle cell proliferation
13. Antiatherogenic activity of nivaldipine, a new potent calcium antagonist
14. Smooth muscle cell migration induced by inflammatory cell products and its inhibition by a potent calcium antagonist, nivaldipine
15. Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery
16. Balloon angioplasty: Natural history of the pathophysiological response to injury in a pig model
17. Fatty streak initiation in Watanabe hyperlipemic and comparably hypercholesterolemic fat-fed rabbits
18. Modèles expérimentaux d'athérosclérose. Apports, limites et perspectives
19. Atherosclerosis in Watanabe heritable hyperlipidaemic rabbits: Evaluation by macroscopic, microscopic and biochemical methods and comparison of atherosclerosis variables
20. Rapid development of atherosclerotic lesions in the rabbit carotid artery induced by perivascular manipulation
21. Arteriosclerosis: The anoxemia theory
22. Enhancing influence of arterial hypoxia on the development of atheromatosis in cholesterol fed rabbits
23. Evidence for an inflammatory basis of coronary arteriosclerosis in the young
24. Arterial intimal hyperplasia after occlusion of the adventitial vasa vasorum in the pig
25. In vivo characterization of a novel calcium entry blocker: SR33805
26. Effect of SR33805 on arterial smooth muscle cell proliferation and neointima formation following vascular injury
27. Characterization of the binding of 3HSR33805 to the slow calcium channel in rat heart sarcolemmal membrane
28. Absence of side effects of hydroxyethylstarch 200 in a porcine model of experimental arterial thrombosis
29. Platelet functions and haemostasis parameters in pigs: Absence of side effects of a procedure of general anaesthesia
30. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the committee on vascular lesions of the council on arteriosclerosis
31. Thrombosis as a factor in the pathogenesis of coronary heart disease
32. The pathogenesis of atherosclerosis
33. Arterial repair and atherosclerosis after mechanical injury. 2: Tissue response after induction of a total local necrosis deep longitudinal injury
34. Role of endothelium and hypercholesterolaemia in intimal thickening and lipid accumulation
35. The porcine model for the understanding of thrombogenesis and atherogenesis
36. The pathogenesis of atherosclerosis. A perspective for the 1990s
37. Cell biology of atherosclerosis
38. A global view on the role of monocytes and platelets in atherogenesis
39. The effects of flow on blood coagulation and thrombosis
40. Endothelium and growth factors in vascular remodeling in hypertension
41. Vascular derived growth factors: Cell biology, pathophysiology and pharmacology
42. Responses of vessel walls to chronically applied electrical stimuli
43. Arterial wall hypoxia following thrombosis of the vasa vasorum is an initial lesion in atherosclerosis
44. The adventitia and atherogenesis: Removal initiates intimal proliferation in the rabbit which regresses on generation of a neoadventitia
45. Proliferation of smooth muscle cells in the inner and outer layers of the tunica, media of arteries
46. Induction of the proliferative phenotype in differentiated myogenic cells by hypoxia
47. Selective expression of platelet derived growth factor B-chain mRNA by human endothelial cells and by human peripheral blood monocytes but not by smooth muscle cells
48. Mechanism of atherogenic action of calcium antagonists
49. Atherosclerosis, calcium and calcium antagonists
50. Calcium antagonists as anti-atherosclerotic agents
51. Cellular processes in atherogenesis: Potential targets of calcium channel blockers
52. Long-term effects of verapamil on aortic smooth muscle cells cultured in the presence of hypercholesterolemic serum
53. Antiatherosclerotic effects of verapamil in primary culture of human aortic intimal cells
54. Antiatherogenic properties of calcium antagonists
55. SIM 6080, a new calcium antagonist, reduces aortic atherosclerosis in cholesterol-fed rabbits
56. The influence of calcium channel blockers on superoxide anions