Angiotensinogen in essential hypertension: From genetics to nephrology

Journal of the American Society of Nephrology

Volumn 12, Issue 3, 2001, Pages 606-615

  Lalouel, J M ^a   Rohrwasser, A ^a   Terreros, D ^a   Morgan, T ^a   Ward, K ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSINOGEN;

ALLELE; ARTICLE; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENETICS; HAPLOTYPE; HEREDITY; HUMAN; HYPOTHESIS; KIDNEY PROXIMAL TUBULE; MOUSE; NEPHROLOGY; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0035122983     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Genetic mechanisms underlying the regulation of urinary sodium excretion and arterial blood pressure: The role of adducin
2. G protein beta3 subunit 825T allele, hypertension, obesity, and diabetic nephropathy
3. Sib pair linkage analysis of renin gene haplotypes in human essential hypertension
4. Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension
5. Molecular basis of human hypertension: Role of angiotensinogen
6. Angiotensinogen: An attractive and underrated participant in hypertension and inflammation
7. Linkage of the angiotensinogen gene to essential hypertension
8. Angiotensinogen in human essential hypertension
9. Evaluation of the angiotensinogen locus in human essential hypertension: A European study
10. Association between the angiotensinogen 235T-variant and essential hypertension in whites: A systematic review and methodological appraisal
11. M235T angiotensinogen gene polymorphism and cardiovascular renal risk
12. Seven lessons from two candidate genes in human essential hypertension: Angiotensinogen and epithelial sodium channel
13. Angiotensinogen as a risk factor for essential hypertension in Japan
14. Angiotensinogen gene and essential hypertension in the Japanese: Extensive association study and meta-analysis on six reported studies
15. Molecular variants of the angiotensinogen gene and hypertension in a Japanese population
16. Association analysis of a polymorphism of the angiotensinogen gene with essential hypertension in Japanese
17. Effect of the angiotensinogen gene Met235→Thr variant on blood pressure and other cardiovascular risk factors in two Japanese populations
18. A molecular variant of angiotensinogen associated with preeclampsia
19. Haplotypes of angiotensinogen in essential hypertension
20. Angiotensinogen
21. Biological implications of a 3 Å structure of dimeric antithrombin
22. X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins
23. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
24. Role of cysteine residues in human angiotensinogen: Cys232 is required for angiotensinogen-pro major basic protein complex formation
25. Characterization of a human angiotensinogen cleaved in its reactive center loop by a proteolytic activity from Chinese hamster ovary cells
26. Structure and expression of the human angiotensinogen gene: Identification of a unique and highly active promoter
27. Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter
28. Angiotensinogen gene polymorphism near transcription start site and blood pressure: Role of a T-to-C transition at intron I
29. Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice
30. Genetic control of blood pressure and the angiotensinogen locus
31. Angiotensinogen T235 expression is elevated in decidual spiral arteries
32. The renin-angiotensin-aldosterone system for normal regulation of blood pressure and sodium and potassium homeostasis
33. Kinetics of the human renin and human substrate reaction
34. Angiotensinogen concentrations and renin clearance: Implications for blood pressure regulation
35. Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake
36. Subpressor angiotensin infusion, renal sodium handling, and salt-induced hypertension in the dog
37. Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla
38. Intrarenal angiotensinogen: Localization and regulation
39. Intrarenal and circulating angiotensin II and renal function
40. Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat
41. Proximal tubular secretion of angiotensin II in rats
42. Angiotensin I-converting enzyme activity in tubular fluid along the rat nephron
43. Intrarenal production of angiotensin II
44. Regulation of proximal tubule transport by angiotensin II
45. Angiotensin II stimulation of hydrogen ion secretion in the rat early proximal tubule: Modes of action, mechanism, and kinetics
46. Effects of angiotensin II on electrolyte transport in the early and late distal tubule in rat kidney
47. Immunohistochemical localization of ANG II AT1 receptor in adult rat kidney using a monoclonal antibody
48. Elements of a paracrine tubular renin-angiotensin system along the entire nephron
49. A conditionally immortalized cell line from murine proximal tubule
50. Proximal tubular fluid levels of angiotensinogen in anesthetized rats
51. Angiotensin II immunoreactivity coexists with renin in the juxtaglomerular granular cells of the kidney
52. Renin in the human kidney: Immunohistochemical localization
53. Immunocytochemistry of the renin-angiotensin system: Renin, angiotensinogen, angiotensin I, angiotensin II, and converting enzyme in the kidneys of mice, rats, and tree shrews
54. Vascular and tubular renin in the kidneys of mice
55. Study of the rat adrenal renin-angiotensin system at a cellular level
56. Further evidence for an inverse relationship between macula densa NaCl concentration and filtration rate