Modulation of biosynthesis of phosphatidylcholine via CDP-choline in rat liver: Influence of ethanol on the microsomal cholinephosphotransferase activity

Molecular and Cellular Biochemistry

Volumn 217, Issue 1-2, 2001, Pages 43-50

  Carrasco, M P ^a   Segovia, J L ^a   Marco, C ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

Cholinephosphotransferase; Ethanol; Liver; Microsomes; Phosphatidylcholine; Rat

Indexed keywords

ALCOHOL; ALKANOL; CARBON; CHOLINE KINASE; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; CHOLINEPHOSPHOTRANSFERASE; CITICOLINE; MICROSOME ENZYME; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; IN VITRO STUDY; INCUBATION TIME; LIVER MICROSOME; MALE; MICROSOME MEMBRANE; MODULATION; NONHUMAN; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; RAT; TEMPERATURE DEPENDENCE;

ALCOHOLS; ANIMALS; CHOLINE KINASE; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; CYTIDINE DIPHOSPHATE CHOLINE; DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE; ETHANOL; KINETICS; LIVER; MALE; MICROSOMES, LIVER; PHOSPHATIDYLCHOLINES; RATS; RATS, SPRAGUE-DAWLEY; TEMPERATURE;

ANIMALIA; ARRHENIUS;

EID: 0035122876     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007271915160     Document Type: Article

References (30)

1. Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon
2. Studies on phospholipid biosynthesis in hepatocytes from alcoholic rats by using radiolabelled exogenous precursors
3. An in vitro model of ethanol-dependent liver cell injury
4. Incorporation of exogenous precursors into neutral lipids and phospholipids in rat hepatocytes: Effect of ethanol in vitro
5. Evidence of differential effects produced by ethanol on specific phospholipid biosynthetic pathways in rat hepatocytes
6. Drug tolerance in biomembranes: A spin label study of the effects of ethanol
7. Ethanol-induced changes in neuronal membrane order. An NMR study
8. Direct NMR evidence for ethanol binding to the lipid-water interface of phospholipid bilayers
9. Interfacial dehydratation by alcohols: Hydrogen bonding of alcohols to phospholipids
10. + current expressed in Xenopus oocytes
11. 13C NMR multiplet relaxation study
12. Fatty acids promote translocation of CPT:phosphocholine cytidylyltransferase to the endoplasmic reticulum and stimulate rat hepatic phosphatidylcholine synthesis
13. Activities of the phosphatidylcholine biosynthetic enzymes in rat liver during development
14. Choline-phosphate cytidylyltransferase
15. CTP-phosphocholine cytidylyltransferase from rat liver
16. Cholinephosphotransferase from mammalian sources
17. Protein measurement with the Folin phenol reagent
18. Acyl chain length dependency of diacylglycerol cholinephosphotransferase and diacylglycerol ethanolamine-phosphotransferase
19. Cloning and expression of human choline/ethanolaminephosphotransferase: Synthesis of phosphatidylcholine and phosphatidylethanolamine
20. Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth
21. Phospholipid synthesis in isolated fat cells
22. Phosphatidylcholine cycle and regulation on phosphatidylcholine biosynthesis by enzyme translocation
23. Persistence of the effects of ethanol in vitro on the lipid order and enzyme activities of chick-liver membranes
24. Inhibitory effect of ethanol on the Na(+)-ATPase activity of rat kidney proximal tubular cell plasma membranes
25. Inhibition by ethanol of excitatory amino acid receptors in rat locus coeruleus neurons in vitro
26. Mechanism by which ethanol inhibits phosphatidylcholine biosynthesis in human leukemic monocyte-like U937 cells
27. Adaptation mechanisms of microorganims to the toxic effects of organic solvents on membranes
28. The membrane actions of anesthetics and tranquilizers
29. Interactions of cyclic hydrocarbons with biological membranes
30. A relationship between alcohol intoxication and the disordering of brain membranes by a series of short-chain alcohols