Biomimetic total synthesis of quinolactacin B, TNF production inhibitor, and its analogs [2]

Journal of Antibiotics

Volumn 54, Issue 1, 2001, Pages 109-112

  Tatsuta, K ^a   Misawa, H ^a   Chikauchi, K ^a  

^a WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID; ARGININE; GLUTAMIC ACID; PROLINE; QUINOLACTACIN B DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SILICA GEL; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VALINE; QUINOLACTACIN B; QUINOLONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

CHEMICAL REACTION; CONTROLLED STUDY; CYCLIZATION; DEHYDRATION; DRUG STRUCTURE; DRUG SYNTHESIS; LETTER; MELTING POINT; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; BIOCHEMISTRY; DRUG ANTAGONISM; METHODOLOGY; SYNTHESIS;

BIOCHEMISTRY; QUINOLONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035122816     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.54.109     Document Type: Letter

References (6)

1. Quinolactacins A, B and C: Novel quinolone compounds from Penicillium sp. EPF-6. I. Taxonomy, production, isolation and biological properties
2. Quinolactacins A, B and C: Novel quinolone compounds from Penicillium sp. EPF-6. II. Physico-chemical properties and structure elucidation
3. An efficient and mild lactonization method for the synthesis of macrolides
4. Syntheses of macrolide antibiotics. III. Direct ester and lactone synthesis from S-tert-butyl thioate (thiol ester)
5. Copper(I)-promoted condensation of α-amino acids with β-keto thio esters: Synthesis of N-acylated L-leucine derivatives containing (S)-4-hydroxy-5-methyl- and (S)-4-hydroxy-2,5-dimethyl-3-oxohexanoic acid
6. Further reactions of t-butyl 3-oxobutanthioate and t-butyl 4-diethylphosphono-3-oxobutanthioate: Carbonyl coupling reactions, amination, use in the preparation of 3-acyltetramic acids and application fuligorubin A