Expression profiling of pancreatic β-cells glucose regulation of secretory and metabolic pathway genes

Diabetes

Volumn 50, Issue SUPPL. 1, 2001, Pages

  Webb, Gene C ^a   Akbar, Murtaza S ^a   Zhao, Chongjian ^a   Steiner, Donald F ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

CELL CULTURE; CONFERENCE PAPER; ENDOPLASMIC RETICULUM; EXPRESSED SEQUENCE TAG; GENE CLUSTER; GENE EXPRESSION REGULATION; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLYCOLYSIS; INSULIN RELEASE; INSULIN SYNTHESIS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 0035122492     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.2007.s135     Document Type: Conference Paper

References (8)

1. Translational control of proinsulin synthesis by glucose
2. Translational control of insulin biosynthesis: Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose
3. Genetics of non-insulin-dependent (type-II) diabetes mellitus
4. Parallel reduction of pancreas insulin content and insulin secretion in 48-h tolbutamide-infused normoglycemic rats
5. The biosynthesis of the subtilisin-related pro-protein convertase PC3, but not that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets
6. Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets
7. Insulin-secreting cell lines: Classification, characteristics and potential applications
8. Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms