Effects ofamino acids and chirality for molecular folding of desoxazoline-ascidiacyclamide derivatives: X-ray crystal structures of four cyclic octapeptidesincluding unusual amino acids, cyclo(-lle-aThr-D-Val-Thz-)2, cyclo(-Ala-aThr-D-Val-Thz-lle-aThr-D-Val-Thz-), cyclo(-Val-aThr-D-Val-Thz-lle-aThr-D-Val-Thz-), and cyclo(-lle-aThr-Val-Thz-lle-aThr-D-Val-Thz-)

Biopolymers

Volumn 58, Issue 3, 2001, Pages 295-304

  Asano, Akiko ^a   Doi, Mitsunobu ^a   Kobayashi, Kiyomi ^a   Arimoto, Masao ^a   Ishida, Toshimasa ^a   Katsuya, Yoshio ^b   Mezaki, Yoshihiro ^b   Hasegawa, Hiroshi ^c   Nakai, Masamichi ^c   Sasaki, Masahiro ^c   Taniguchi, Taizo ^c   Terashima, Akira ^c  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Hyogo Prefectural Institute of Industrial Research Technical Center for Machinery and Metals   (Japan)

^c Institute for Aging Brain and Cognitive Disorders   (Japan)

Author keywords

Allo threonine; Asymmetry; Chirality; Epimer; Molecular folding; Oxazoline ring; Patellamide; X ray structure

Indexed keywords

AMINO ACIDS; CELLULOSE DERIVATIVES; CONFORMATIONS; CRYSTAL ORIENTATION; MOLECULAR DYNAMICS; X RAY CRYSTALLOGRAPHY;

CHIRALITY; OXAZOLINE RING;

POLYPEPTIDES;

AMIDE; AMINO ACID; DESOXAZOLINE ASCIDIACYLAMIDE DERIVATIVE; ISOLEUCINE; OCTAPEPTIDE; PATELLAMIDE D; THREONINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; CHIRALITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

AMINO ACIDS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; PROTEIN FOLDING;

EID: 0035121841     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0282(200103)58:3<295::AID-BIP1006>3.0.CO;2-X     Document Type: Article

References (31)