Circumvention of herd immunity during an outbreak of meningococcal disease could be correlated to escape mutation in the porA gene of Neisseria meningitidis

Infection and Immunity

Volumn 69, Issue 3, 2001, Pages 1971-1973

  Taha, M K ^a   Bichier, E ^a   Perrocheau, A ^a   Alonso, J M ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; GENE PRODUCT; PORIN A; UNCLASSIFIED DRUG;

ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; CORRELATION FUNCTION; DISEASE PREDISPOSITION; EPIDEMIC; GENE MUTATION; HUMAN; IMMUNITY; MENINGOCOCCOSIS; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; SERUM; STRAIN DIFFERENCE;

DISEASE OUTBREAKS; EPIDEMIOLOGY, MOLECULAR; FRANCE; HUMANS; MENINGOCOCCAL INFECTIONS; MENINGOCOCCAL VACCINES; MOLECULAR SEQUENCE DATA; MUTATION; NEISSERIA MENINGITIDIS; POLYMERASE CHAIN REACTION; PORINS; SEQUENCE ANALYSIS, DNA;

EID: 0035115860     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.3.1971-1973.2001     Document Type: Article

References (10)

1. Neisseria meningitidis group B sero-subtying using monoclonal antibodies in whole-cell ELISA
2. Global epidemiology of meningococcal disease
3. Meningococcal carriage and disease
4. Clonal diversity of Neisseria meningitidis from a population of asymptomatic carriers
5. Rapid epidemiological characterization of Neisseria meningitidis using polymerase chain reaction from biological samplings
6. Microevolution through DNA exchange among strains of Neisseria meningitidis isolated during an outbreak in the Czech Republic
7. Point mutation in meningococcal porA gene associated with increased endemic disease
8. Protective efficacy of monoclonal antibodies to class 1 and class 3 outer membrane proteins of Neisseria meningitidis B:15:P1.16 in infant rat infection model: New prospects for vaccine development
9. Increased sensitivity of gonococcal pilA mutants to bactericidal activity of normal human serum
10. Mechanisms of neisserial serum resistance