Immunolocalisation of cytochrome P-450 3A enzymes in human breast carcinoma: Relationship with tumour differentiation and steroid receptors

Pharmacology and Toxicology

Volumn 88, Issue 3, 2001, Pages 142-146

  Galant, Christine ^a   Gala, Jean Luc ^a   Van Den Berge, Véronique ^a   Berlière, Martine ^a   Haumont, Esther ^a   Horsmans, Yves ^a  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; KI 67 ANTIGEN; STEROID RECEPTOR;

ANTIBODY LABELING; ARTICLE; BREAST CARCINOMA; CANCER GROWTH; CANCER SUSCEPTIBILITY; CELL PROLIFERATION; ENZYME LOCALIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METABOLISM; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR DIFFERENTIATION; XENOBIOTIC METABOLISM;

ANTIBODIES, MONOCLONAL; ARYL HYDROCARBON HYDROXYLASES; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CARCINOMA, LOBULAR; CELL TRANSFORMATION, NEOPLASTIC; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; OXIDOREDUCTASES, N-DEMETHYLATING; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0035113311     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2001.d01-95.x     Document Type: Article

References (5)

1. Aoyama, T., K. Korzkwa, K. Nagata, J. Gillette, H. V. Gelboin & F. J. Gonzalez: Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s. Endocrinology 1990, 126, 3101-3106.
2. Beaune, P. H., P. Kremers F. Letawe-Grougon & J. E. Gielen: Monoclonal antibodies against human liver cytochrome P-450. Biochem. Pharmacol 1985, 34, 3547-3552.
3. Bertilsson, G., J. Heidrich, K. Svensson, M. Asman, L. Jendeberg, M. Sydow-Backman, R. Ohlsson, H. Postlind, P. Blomquist & A. Berkenstam: Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc. Natl. Acad. Sei. USA 1998, 95, 12208-12213.
4. Ching, K. Z., K. A. Tenney, J. Chen & E. T. Morgan: Suppression of constitutive cytochrome P450 gene expression by epidermal growth factor receptor ligands in cultured rat hepatocytes. Drug Metab. Dispos. 1996, 24, 542-546.
5. Dickson, R. B.: The molecular basis of breast cancer In: Molecular biology in cancer medicine. Eds. R. Kuzrock, M. Talpaz. Martin Dunitz Ltd, London: 1995, pp. 241-272.