Estrogen derivative relaxes rabbit aorta via the endothelial receptor system

Italian Heart Journal

Volumn 2, Issue 1, 2001, Pages 49-54

  Raddino, R ^a   Pela G ^a   Uberti, D ^a   Portera, C ^a   Ferrari, R ^a   Scarabelli, T M ^a   Cooper, T J ^a   Manca, C ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Estrogen; Nitric oxide; Rabbit aorta; Tamoxifen; Vascular estrogen receptors

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN; CALCIUM; CELL RECEPTOR; DIETHYLSTILBESTROL; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; POTASSIUM; POTASSIUM CHLORIDE; SEROTONIN; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL TONE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; NONHUMAN; RABBIT; SPASMOLYSIS; VASCULAR ENDOTHELIUM; VASODILATATION;

ANIMALS; AORTA; DIETHYLSTILBESTROL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ESTROGENS, NON-STEROIDAL; FEMALE; RABBITS; RECEPTORS, ESTROGEN; VASODILATOR AGENTS;

EID: 0035113006     PISSN: 1129471X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Estrogen and coronary heart disease in women
2. Menopause and the risk of coronary heart disease in women
3. Menopause and risk of cardiovascular disease. The Framingham study
4. Postmenopausal estrogen therapy and cardiovascular disease: Ten year follow-up from the Nurses Health Study
5. Decreased mortality in users of estrogen replacement therapy
6. Hormone therapy to prevent disease and prolong life in postmenopausal women
7. Cholesterol, lipoproteins, and coronary heart disease in women
8. Inhibition of coronary artery atherosclerosis by 17-β estradiol in ovariectomized monkeys: Lack of an effect of added progesterone
9. 2 in porcine coronary artery
10. Vascular effects of 17β-estradiol in male Sprague-Dawley rats
11. Nitric oxide accounts for dose-dependent estrogen-mediated coronary relaxation after acute estrogen withdrawal
12. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: Implications for atherosclerosis
13. Estrogen-induced uterine vasodilation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis
14. Influence of sex hormones on plasma endothelin levels
15. Short-term administration of estrogen and vascular responses of atherosclerotic coronary arteries
16. Endothelial-dependent coronary vasomotor responsiveness in postmenopausal women with and without estrogen replacement therapy
17. 17β-estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease
18. Estradiol-binding sites in rat aortic smooth muscle cells in culture
19. Vascular smooth muscle cells target for estrogen
20. How do we explain the clinical benefits of estrogen?
21. Cell-surface estrogen receptors mediate calcium-dependent nitric oxide release in human endothelia
22. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetyl-choline
23. Cumulative dose-response curves. Technique for making the dose-response curves in isolated organs and the evaluation of drugs parameters
24. Effects of calcium entry blockers not connected with calcium channel inhibition
25. Mechanism of action of human calcitonin gene-related peptide in rabbit heart and in human mammary arteries
26. Estrogeni e progestinici
27. Towards a molecular understanding of the atheroprotective effects of estrogens: A review of estrogen effects on endothelial activation
28. Acute vascular effects of estrogen in postmenopausal women
29. The mitogenic effect of 17beta-estradiol on in vitro endothelial cell proliferation and on in vivo reendothelialization are both dependent on vascular endothelial growth factor
30. Effects of estrōgen replacement therapy on peripheral vasomotor function in postmenopausal women
31. 17 Beta-oestradiol enhances nitric oxide synthase activity in endothelium-denuded rat aorta
32. 17Beta-estradiol reduces vasoconstriction in endothelium-denuded rat aortas through inducible NOS
33. Estrogen upregulates endothelial nitric oxide synthase gene expression in fetal pulmonary artery endothelium
34. Estrogen receptor alpha mediates the non genomic activation of endothelial nitric oxide synthase by estrogen
35. Estrogen relaxes coronary arteries by opening BKCa-channels through a cGMP dependent mechanism
36. Effects of 17β-estradiol on the isolated rabbit heart
37. Action of steroid sex hormones on the isolated rabbit heart
38. Effect of 17-beta estradiol in the rabbit: Endothelium-dependent and -independent mechanisms of vascular relaxation
39. Effect of 17β-oestradiol on cytokine-induced nitric oxide production in rat isolated aorta
40. Post-menopausal hormone replacement therapy and the vascular wall: Mechanisms of 17 beta-estradiol's effects on vascular biology
41. Estrogen increases endothelial nitric oxide by a receptor-mediated system
42. The vascular protective effects of estrogen
43. Voltage-activated potassium but not calcium currents in cultured bovine aortic endothelial cells
44. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
45. Role of cyclic-GMP in relaxation of vascular smooth muscle
46. Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women
47. Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women