Heat shock-mediated transient increase in intracellular 3′, 5′-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation

Clinical and Experimental Metastasis

Volumn 18, Issue 2, 2000, Pages 131-138

  Sawaji, Yasunobu ^a   Sato, Takashi ^a   Seiki, Motoharu ^b   Ito, Akira ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

cAMP; Gelatinase A; Heat shock; Human fibroblasts; Human fibrosarcoma cells; MT1 MMP; Tumor invasion

Indexed keywords

BUCLADESINE; CONCANAVALIN A; CYCLIC AMP; FORSKOLIN; GELATINASE A; HEAT SHOCK PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; CANCER INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVITY; EXTRACELLULAR SPACE; FIBROSARCOMA; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; POLYACRYLAMIDE GEL ELECTROPHORESIS; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; SQUAMOUS CELL CARCINOMA;

BUCLADESINE; CYCLIC AMP; ENZYME ACTIVATION; ENZYME PRECURSORS; FORSKOLIN; GELATINASES; HEAT-SHOCK RESPONSE; HUMANS; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0035112349     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006760021997     Document Type: Article

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