In vivo absorption studies of insulin from an oral delivery system

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 8, Issue 1, 2001, Pages 19-23

  Jerry, N ^a   Anitha, Y ^a   Sharma, C P ^a   Sony, P ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Alginate; In Vivo Absorption; Insulin; Microspheres; Oral Drug Delivery

Indexed keywords

ALGINIC ACID; BETA CYCLODEXTRIN; INSULIN; IP; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG EFFECT; EMULSION; GASTROINTESTINAL ABSORPTION; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; INSULIN TREATMENT; NONHUMAN; PH; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

ADMINISTRATION, ORAL; ALGINATES; ANIMALS; BETA-CYCLODEXTRINS; BIOCOMPATIBLE MATERIALS; BLOOD GLUCOSE; CYCLODEXTRINS; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; INSULIN; INTESTINAL ABSORPTION; LIPOSOMES; MICROSPHERES; RADIOIMMUNOASSAY; RATS; TIME FACTORS;

EID: 0035111623     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/107175401300002711     Document Type: Article

References (17)

1. Biochemical and morphocytochemical evidence for the intestinal absorption of insulin in control and diabetic rats - Comparison between the effectiveness of duodenal and colon mucosa
2. Controlled release of insulin from polymer matrices - Control of diabetes in rats
3. Liposomes as a carrier for administration of insulin: Effect of formulation factors
4. Insulin in w/o/w multiple emulsion biological activity after oral administration in normal and diabetic rats
5. Modulation of insulin release from chitosan/alginate microspheres
6. Modulation of some gluconeogenic enzyme activities in diabetic rat liver and kidney: Effect of antidiabetic compounds
7. Chitosan/calcium alginate beads for oral delivery of insulin
8. Oral drag delivery system for insulin based on alginate microparticles: Preparation, characterisation, in-vitro and in-vivo evaluation
9. Blood glucose control in diabetic rats by transdermal iontophoretic delivery of insulin
10. 2 in solution
11. Improvement to some pharmaceutical properties of Flurbiprofen by β- and γ -cyclodextrins in humans
12. Drugs producing diabetes through damage of the insulin secreting cells
13. Microparticle resins as a potential nasal drug delivery system for insulin
14. Improvement of oral bioavailability of prednisolone by β-cyclodextrin complexation in humans
15. Development, characterization and evaluation of an autoregulatory delivery system for insulin
16. Absorption enhancement of polypeptide drugs by cyclodextrins. I. Enhanced rectal absorption of insulin from hollow-type suppositories containing insulin and cyclodextrins in rabbits