Extreme elevation of maternal serum alpha-fetoprotein associated with mosaic trisomy 8 in a liveborn

Fetal Diagnosis and Therapy

Volumn 16, Issue 2, 2001, Pages 120-122

  Miller, R I ^a   Stephan, M J ^a   Hume, R F ^a   Walker, W O ^a   Kelly, P ^a   Calhoun, B C ^a   Hoeldtke, N J ^a   Hayden, J E ^a   Martin, L S ^a,b  

^a MADIGAN ARMY MEDICAL CENTER   (United States)

^b NONE   (United States)

Author keywords

Fetal dysmorphism; Maternal serum alpha fetoprotein; Maternal serum analytes; Mosaic trisomy 8

Indexed keywords

ALPHA FETOPROTEIN;

AORTA VALVE DISEASE; APGAR SCORE; ARTICLE; BRAIN THIRD VENTRICLE; CASE REPORT; CHROMOSOME MOSAICISM; CLINICAL FEATURE; CLINODACTYLY; CORNEA OPACITY; CORPUS CALLOSUM AGENESIS; CRYPTORCHISM; FACE ASYMMETRY; HUMAN; KARYOTYPE 46,XY; LEUKEMIA; MALE; MATERNAL SERUM; NEWBORN; PLAGIOCEPHALY; PRIORITY JOURNAL; SYNDACTYLY; TRISOMY 8; TROPHOBLASTIC DISEASE;

ADULT; ALPHA-FETOPROTEINS; AORTIC VALVE; CHROMOSOMES, HUMAN, PAIR 8; CORPUS CALLOSUM; CRYPTORCHIDISM; FACIAL ASYMMETRY; FEMALE; FINGERS; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; MALE; MOSAICISM; PREGNANCY; PREGNANCY OUTCOME; SYNDACTYLY; TOES; TRISOMY;

EID: 0035108625     PISSN: 10153837     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053894     Document Type: Article

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3. A three-year follow-up on a child with low level trisomy 8 mosaicism which was diagnosed prenatally
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14. Why might maternal serum AFP behigh in pregnancies in which the fetus is normally formed?
15. Constitutional trisomy 8 mosaicism and gestational trophoblastic disease
16. Survival of trisomy 8 correlates with somatic origin of the trisomy
17. Molecular studies of the aetiology of trisomy 8 in spontaneous abortions and the liveborn population
18. Meiotic origin of trisomy in confined placental mosaicism is correlated with presence of fetal uniparental disomy, high levels of trisomy in trophoblast, and increased risk of fetal intrauterine growth restriction