Digitoxin-like immunoreactivity in sera of mice after feeding with chinese medicine Chan Su: Study of protein binding of Chan Su in normal sera, uremic sera and sera from patients with liver disease

Clinica Chimica Acta

Volumn 305, Issue 1-2, 2001, Pages 175-179

  Dasgupta, Amitava ^a   Galvao Neto, Antonio L ^a   Wells, Alice ^a   Olsen, Margaret ^a   Actor, Jeffrey K ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Chan Su; Digitoxin like immunoreactivity; Liver disease; Protein binding; Uremia

Indexed keywords

ALBUMIN; BUFADIENOLIDE; CARDIOTONIC AGENT; CHINESE DRUG; DIGITOXIN; SERUM ALBUMIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHAN SU; CHINESE MEDICINE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG PROTEIN BINDING; FLUORESCENCE POLARIZATION IMMUNOASSAY; IMMUNOREACTIVITY; LIVER DISEASE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SERUM; ULTRAFILTRATION; UREMIA;

ANIMALS; BUFANOLIDES; DIGITOXIN; LIVER DISEASES; MICE; UREMIA;

ANURA;

EID: 0035108240     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(01)00377-1     Document Type: Article

References (12)

1. Unconventional medicines in the United States: Prevalence, cost, and patterns of use
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3. Examination for toxicity of a Chinese drug, the total glandular secretion product Chan Su in pregnant mice and embryos
4. Pharmacology and toxicology of toad venom
5. Pharmacological actions of 'Kyushin', a drug containing toad venom: Cardiotonic and arrhythmogenic effects and excitatory effect on respiration
6. Effect of three sodium-potassium adenosine triphosphate inhibitors
7. Lethal ingestion of Chinese tea containing Chan Su
8. Digoxin concentration in blood
9. Bufalin and unidentified substances in traditional Chinese medicine cross react in commercial digoxin assay
10. Rapid detection of cardioactive bufalin toxicity using fluorescence polarization immunoassay for digoxin
11. Falsely elevated serum digitoxin concentrations due to cross reactivity of water extractable digitoxin-like immunoreactivity of Chinese medicine Chan Su: Elimination of interference by use of a chemiluminescent assay
12. Sensitive methods for determination of free digitoxin concentration using digitoxin immunoassays: Demonstration of elevated free digitoxin concentration due to digitoxin-phenytoin interaction by applying these new techniques