Prenatal exposure to a maternal low protein diet shortens life span in rats

Gerontology

Volumn 47, Issue 1, 2001, Pages 9-14

  Aihie Sayer, Avan ^a,b   Dunn, Rebecca ^b   Langley Evans, Simon ^c   Cooper, Cyrus ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF NORTHAMPTON   (United Kingdom)

Author keywords

Diet restriction; Low protein diet, prenatal

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIRTH WEIGHT; CONTROLLED STUDY; DIET; EUTHANASIA; FEMALE; FOOD INTAKE; INTRAUTERINE GROWTH RETARDATION; LIFESPAN; MALE; MALNUTRITION; MATERNAL NUTRITION; NEWBORN; NONHUMAN; PERINATAL PERIOD; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN RESTRICTION; RAT; SYSTOLIC BLOOD PRESSURE; WEANING; WEIGHT GAIN;

ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; DIET, PROTEIN-RESTRICTED; FEMALE; LIFE EXPECTANCY; NUTRITION PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; SURVIVAL ANALYSIS;

EID: 0035107258     PISSN: 0304324X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000052764     Document Type: Article

References (29)

1. Effect of dietary restriction on lifespan
2. Slowing ageing by caloric restriction
3. Undernutrition and aging
4. Are rates of ageing determined in utero?
5. Weight in infancy and prevalence of coronary heart disease in adult life
6. Initiation of hypertension in utero and its amplification throughout life
7. Fetal and infant growth and impaired glucose tolerance at age 64 years
8. Childhood growth, physical activity, and peak bone mass in women
9. Programming by early nutrition in man
10. Maternal nutrition in early and late pregnancy in relation to placental and fetal growth
11. Diet in pregnancy and the offspring's blood pressure 40 years later
12. Nutritional programming and the development of hypertension
13. Fetal exposure to maternal low protein diets impairs nephrogenesis and promotes hypertension in the rat
14. Evidence of progressive deterioration of renal function in rats exposed to a maternal low protein diet in utero
15. The acute phase response of adult rats is altered by in utero exposure to maternal low protein diets
16. Effect of dietary restriction of pregnant rats on body weight gain of the offspring
17. Embryogenic effect on post-natal changes in hemoglobin concentration with time
18. Effect of the level of nutrition on rates of cell proliferation and of RNA and protein synthesis in the rat
19. On the growth of relatively long lived compared with that of relatively short lived animals
20. Fishing in the stream of diabetes: From measuring insulin to the control of fetal organogenesis
21. Early growth determines longevity in male rats and may be related to telomere shortening in the kidney
22. Weanling rats exposed to maternal low protein diets during discrete periods of gestation exhibit differing severity of hypertension
23. Early administration of angiotensin-converting enzyme inhibitor captopril, prevents the development of hypertension programmed by intrauterine exposure to a maternal low-protein diet in the rat
24. Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets
25. Early protein restriction and obesity independently induce hypertension in 1-year-old rats
26. Association of disproportionate growth of fetal rats in late gestation with raised systolic blood pressure in later life
27. Impaired growth and increased glucocorticoid-sensitive enzyme activities in tissues of rat fetuses exposed to maternal low protein diets
28. Is lifespan determined in utero?