II. An altered proliferation response due to the anticonvulsant phenytoin (PHT)in epileptic patients

Teratogenesis Carcinogenesis and Mutagenesis

Volumn 21, Issue 2, 2001, Pages 151-164

  Kaul, Asha ^a   Kalla, N R ^b   Goyle, Shobha ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Anticonvulsants; Epilepsy; Genotoxicity; Mitotic index; Phenytoin; Proliferation kinetics; Proliferation rate index

Indexed keywords

ANTICONVULSIVE AGENT; PHENYTOIN;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG EFFECT; EPILEPSY; FEMALE; GENETIC TOXICOLOGY; HUMAN; LYMPHOCYTE PROLIFERATION; MALE; MITOSIS INDEX; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGE FACTORS; AGE OF ONSET; ANTICONVULSANTS; CELL CYCLE; CELL DIVISION; CHILD; EPILEPSY; FEMALE; HUMANS; KINETICS; LYMPHOCYTES; MALE; MITOSIS; PHENYTOIN; SEX FACTORS; TIME FACTORS;

EID: 0035105314     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6866(2001)21:2<151::AID-TCM4>3.0.CO;2-E     Document Type: Article

References (18)

1. Mutagenic risk in epileptic patients before and after anticonvulsant therapy
2. Sister chromatid exchange in human chromosomes from normal individuals and epileptic patients on combinations of anticonvulsants
3. Lack of sister chromatid exchange induction in phenytoin-treated patients with epilepsy
4. Comparative effects of phenytoin and/or phenobarbital treatment on sister chromatid exchange
5. The effect of valproic acid on SCE and chromosome aberrations in epileptic children
6. Sister chromatid exchanges are increased in epileptics, but not by sodium valproate
7. Chromosomal investigations in epileptic children during long term therapy with phenytoin or primidone
8. Increased sister chromatid exchanges in epileptic children during long term therapy with phenytoin
9. Chromosomal studies of peripheral blood from epileptic patients treated with phenobarbital and/or diphenylhydantoin
10. In vivo and in vitro evaluation of the mutagenic potential of carbamazepine: Does melatonin have anti mutagenic activity?
11. Genotoxicity of the anticonvulsant drug phenytoin (PHT): A follow up study of PHT-untreated epileptic patients. II. Mitotic index and proliferation kinetics
12. Effects of carbamazepine on human chromosomes
13. Induction of chromosomal aberrations, sister chromatid exchanges and cell cycle delay in cow peripheral blood lymphocytes treatment with two N-nitroso compounds in vitro
14. Mitotic index and lymphocyte proliferation kinetics in testing the genotoxicity of chemical agents
15. Are mitotic index and lymphocyte proliferation kinetics reproducible endpoints in genetic toxicology testing?
16. Analysis of sister chromatid exchanges, cell kinetics and mitotic index in lymphocytes of smoking pesticide sprayers
17. A cytogenetic study of men environmentally and occupationally exposed to airborne pollutants
18. Cytogenetic damage induced in human lymphocytes by sodium bisulfite