Role of chemical mediators in airway hyperresponsiveness in an asthmatic model

Respiration

Volumn 68, Issue 1, 2001, Pages 73-77

  Tohda, Yuji ^a   Muraki, Masato ^a   Kubo, Hirokazu ^a   Itoh, Mari ^a   Haraguchi, Ryuta ^a   Nakajima, Shigenori ^a   Fukuoka, Masahiro ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Airway hyperreactivity; Asthma model; Platelet activating factor; Thromboxane A2

Indexed keywords

ALUMINUM HYDROXIDE; CYCLOPHOSPHAMIDE; DOMITROBAN; HISTAMINE; INDOMETACIN; ISRAPAFANT; LEUKOTRIENE C4; LEUKOTRIENE D4; PRANLUKAST; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2;

AIRWAY PRESSURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; GUINEA PIG; INSPIRATORY CAPACITY; MALE; MEDIATOR; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; VAGUS NERVE;

AIRWAY RESISTANCE; ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HISTAMINE; INDOMETHACIN; LEUKOTRIENE C4; LEUKOTRIENE D4; MALE; OVALBUMIN; PLATELET ACTIVATING FACTOR; PROBABILITY; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; THROMBOXANE A2;

EID: 0035104819     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000050466     Document Type: Article

References (28)

1. International Consensus Report on Diagnosis and Management of Asthma. 1. Definition, diagnosis, and classification
2. Airway responsiveness to histamine and methacholine: Relationship to minimum treatment to control symptoms of asthma
3. Dual-phase response model for bronchial asthma
4. Airway inflammation and airway hyperresponsiveness
5. 3-induced change in bronchial reactivity to methacholine and airway inflammation in humans
6. Respiratory infections and bronchial hyperreactivity
7. Allergen-induced airway hyperresponsiveness
8. Leukotrienes and airway responses
9. 4 enhance histamine responsiveness in asthmatic airways
10. 4 in guinea pigs
11. 4, prostaglandin F and potassium
12. 4 cause widespread and extensive plasma extravasation in the guinea pig
13. 4 and platelet-activating factor on airway reactivity in normal subjects
14. 4 enhance histamine responsiveness in asthmatic airways
15. Ozone-induced bronchial hyperreactivity in guinea pigs is abolished by BW 755C or FPL 55712 but not by indomethacin
16. Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx induced by ozone in dogs
17. 2) in guinea pigs
18. 4 induces airway hyperresponsiveness in dogs
19. Significance of thromboxane generation in ozone-induced airway hyperresponsiveness in dogs
20. Airway hyperresponsiveness induced by platelet-activating factor: Role of thromboxane generation
21. 2 receptor antagonist (AA-2414) on bronchial hyperresponsiveness to methacholine in subjects with asthma
22. Effect of AA-2414 on early and late bronchial responses in actively sensitized guinea pigs
23. The effect of the selective PAF antagonist BN 52021 on PAF- and antigen-induced bronchial hyperreactivity and eosinophil accumulation
24. Inhibitory effects of a novel PAF antagonist E 6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice
25. Modification of allergen-induced airway obstruction and airway hyperresponsiveness in an allergic rabbit model by the selective platelet-activating factor antagonist, BN52021
26. Inhibition of antigen-induced airway hyperresponsiveness, but not acute hypoxia nor airway eosinophilia, by an antagonist of platelet-activating factor
27. Clinical and experimental investigation on muscarinic acetylcholine receptor in bronchial asthma
28. Vagal reflex mediates bronchoconstriction caused by platelet-activating factor