A comparison of insulin suppression tests performed with somatostatin and octreotide with particular reference to tolerability

Diabetes Research and Clinical Practice

Volumn 51, Issue 3, 2001, Pages 187-193

  Hwu, Chii Min ^a,b   Kwok, Ching Fai ^a,b   Chiang, Shu Chiung ^a   Wang, Pi Ying ^a   Hsiao, Li Chuan ^a   Lee, Sheng Hung ^a   Lin, Shu Hsia ^a   Ho, Low Tone ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Insulin suppression test; Octreotide; Somatostatin; Tolerability

Indexed keywords

GLUCOSE; INSULIN; ISOPHANE INSULIN; OCTREOTIDE; SOMATOSAN; SOMATOSTATIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TOLERABILITY; FEMALE; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; METHODOLOGY; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL;

ADULT; BLOOD GLUCOSE; C-PEPTIDE; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INSULIN; INSULIN RESISTANCE; MALE; OCTREOTIDE; REFERENCE VALUES; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SOMATOSTATIN; TIME FACTORS;

EID: 0035104515     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(00)00238-2     Document Type: Article

References (25)

1. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
2. Glucose clamp technique: a method for quantifying insulin secretion and resistance
3. Assessment of insulin resistance with the insulin suppression test and the euglycemic clamp
4. Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes
5. Diabetes and the alpha cell
6. Glucose, insulin and somatostatin infusion for the determination of insulin sensitivity
7. How to measure insulin action in vivo
8. Evaluation of octreotide to assess insulin-mediated glucose disposal by the insulin suppression test
9. Insulin sensitivity test using a somatostatin analogue, octreotide (sandostatin)
10. Modified method using a somatostatin analogue, octreotide acetate (sandostatin) to assess in vivo insulin sensitivity
11. Growth hormone (GH) replacement reduces total body fat and normalizes insulin sensitivity in GH-deficient adults: a report of one-year clinical experience
12. Insulin insensitivity in offspring of parents with type 2 diabetes mellitus
13. Development and validation of a new radioimmunoassay of insulin using semisynthetic human tracer
14. Octreotide: a long-acting inhibitor of endogenous hormone secretion for human metabolic investigations
15. Octreotide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in conditions associated with excessive peptide secretion
16. Systemic and pulmonary haemodynamic effects of somatostatin
17. The effect of somatostatin on central hemodynamics, renal blood flow, and renal function in dogs
18. Somatostatin in acute bleeding oesophageal varices: pharmacology and rationale for use
19. The reproducibility of the insulin sensitivity test (IST) without pancreatic suppression (modified Harano technique) as an index of insulin resistance in non-insulin-dependent diabetic subjects
20. Reproducibility of the measurement of insulin sensitivity by the modified insulin suppression test
21. SMS 201-995: a very potent and selective octapeptide analogues of somatostatin with prolong action
22. Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers